Genomic epidemiology and anti-biofilm mechanisms of Lactobacillus in ST11 carbapenem-resistant Klebsiella pneumoniae in China

Genomic epidemiology and anti-biofilm mechanisms of Lactobacillus in ST11 carbapenem-resistant Klebsiella pneumoniae in China

BackgroundThe ST11 clone of carbapenem-resistant Klebsiella pneumoniae (CRKP) has emerged as a major public health threat, driving hospital outbreaks across China and contributing to chronic infections through robust biofilm formation. The scarcity of effective treatment options poses a critical cha...

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Bibliographic Details
Main Authors: Shuang Li, Duo Zhang, Xindan Zhang, Xiaohan Ma, Shuai Zheng, Di Zhou, Qinlong Hou, Gen Li, Huiming Han
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Microbiology
Subjects:
ST11 Klebsiella pneumoniae
biofilm
Lactobacillus
probiotics
metabolomics
multidrug resistance
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2025.1619621/full
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