Carcinosarcoma of the Rectum: Report of a Rare Colorectal Malignancy and Review of the Literature
Carcinosarcoma (CS) is a rare mixed mesodermal malignancy most commonly affecting the female reproductive organs, respiratory tract, head, and neck. Though infrequent, it may affect the gastrointestinal tract, most often the oesophagus and only very rarely the rectum. Histologically, it is composed...
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Case Reports in Surgery |
| Online Access: | http://dx.doi.org/10.1155/2015/412918 |
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| author | Alexis Sudlow Ming Ho Liu Geoffrey Waters Vamsi R. Velchuru |
| author_facet | Alexis Sudlow Ming Ho Liu Geoffrey Waters Vamsi R. Velchuru |
| author_sort | Alexis Sudlow |
| collection | DOAJ |
| description | Carcinosarcoma (CS) is a rare mixed mesodermal malignancy most commonly affecting the female reproductive organs, respiratory tract, head, and neck. Though infrequent, it may affect the gastrointestinal tract, most often the oesophagus and only very rarely the rectum. Histologically, it is composed of two distinct elements of epithelial and mesenchymal origin. Clinically, it is a very aggressive tumour with many patients presenting with metastatic lymph nodes or distant metastases at the time of diagnosis. Prognosis is poor despite intervention with the majority of patients dying within six months. Due to the rarity of this condition, there are no specific treatment guidelines presently available. We describe the case of an 80-year-old patient with carcinosarcoma of the rectum with discussion of the immunohistochemistry and review the available literature pertaining to this rare presentation. |
| format | Article |
| id | doaj-art-ba0d38a223b14687a38c97e766a0b4ff |
| institution | Kabale University |
| issn | 2090-6900 2090-6919 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Surgery |
| spelling | doaj-art-ba0d38a223b14687a38c97e766a0b4ff2025-02-03T05:55:17ZengWileyCase Reports in Surgery2090-69002090-69192015-01-01201510.1155/2015/412918412918Carcinosarcoma of the Rectum: Report of a Rare Colorectal Malignancy and Review of the LiteratureAlexis Sudlow0Ming Ho Liu1Geoffrey Waters2Vamsi R. Velchuru3Department of Colorectal Surgery, James Paget University Hospital, Gorleston NR31 6LA, UKDepartment of Colorectal Surgery, James Paget University Hospital, Gorleston NR31 6LA, UKDepartment of Histopathology, Norfolk and Norwich University Hospital, Norwich NR4 7UY, UKDepartment of Colorectal Surgery, James Paget University Hospital, Gorleston NR31 6LA, UKCarcinosarcoma (CS) is a rare mixed mesodermal malignancy most commonly affecting the female reproductive organs, respiratory tract, head, and neck. Though infrequent, it may affect the gastrointestinal tract, most often the oesophagus and only very rarely the rectum. Histologically, it is composed of two distinct elements of epithelial and mesenchymal origin. Clinically, it is a very aggressive tumour with many patients presenting with metastatic lymph nodes or distant metastases at the time of diagnosis. Prognosis is poor despite intervention with the majority of patients dying within six months. Due to the rarity of this condition, there are no specific treatment guidelines presently available. We describe the case of an 80-year-old patient with carcinosarcoma of the rectum with discussion of the immunohistochemistry and review the available literature pertaining to this rare presentation.http://dx.doi.org/10.1155/2015/412918 |
| spellingShingle | Alexis Sudlow Ming Ho Liu Geoffrey Waters Vamsi R. Velchuru Carcinosarcoma of the Rectum: Report of a Rare Colorectal Malignancy and Review of the Literature Case Reports in Surgery |
| title | Carcinosarcoma of the Rectum: Report of a Rare Colorectal Malignancy and Review of the Literature |
| title_full | Carcinosarcoma of the Rectum: Report of a Rare Colorectal Malignancy and Review of the Literature |
| title_fullStr | Carcinosarcoma of the Rectum: Report of a Rare Colorectal Malignancy and Review of the Literature |
| title_full_unstemmed | Carcinosarcoma of the Rectum: Report of a Rare Colorectal Malignancy and Review of the Literature |
| title_short | Carcinosarcoma of the Rectum: Report of a Rare Colorectal Malignancy and Review of the Literature |
| title_sort | carcinosarcoma of the rectum report of a rare colorectal malignancy and review of the literature |
| url | http://dx.doi.org/10.1155/2015/412918 |
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