A Case of Phenibut Withdrawal Management and Detoxification Using Baclofen in the Outpatient Setting
Phenibut, a GABAB receptor agonist, has surged in popularity due to its nootropic and anxiolytic effects. Despite not being FDA approved, it is accessible online due to its marketing as a dietary supplement, leading to unregulated distribution. Increasing reports have highlighted the risks of addict...
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2024-01-01
|
| Series: | Case Reports in Psychiatry |
| Online Access: | http://dx.doi.org/10.1155/2024/8824770 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832559305489907712 |
|---|---|
| author | Emma DiFiore Julie Pittman |
| author_facet | Emma DiFiore Julie Pittman |
| author_sort | Emma DiFiore |
| collection | DOAJ |
| description | Phenibut, a GABAB receptor agonist, has surged in popularity due to its nootropic and anxiolytic effects. Despite not being FDA approved, it is accessible online due to its marketing as a dietary supplement, leading to unregulated distribution. Increasing reports have highlighted the risks of addiction and severe withdrawal symptoms associated with phenibut use. This case report explores the management of phenibut withdrawal in an outpatient setting using a baclofen taper. The slow taper was complicated by various withdrawal symptoms, and the patient was ultimately stabilized on lorazepam, baclofen, gabapentin, and clonidine after 5-months time. This case is unique, as it also highlights challenges in tapering off baclofen following phenibut detoxification. The study underscores the need for further research on the pharmacological management of phenibut withdrawal, emphasizing the importance of raising awareness about phenibut’s dangers and associated clinical presentations. |
| format | Article |
| id | doaj-art-ba0ac60fabfd4d548af912b0c685701e |
| institution | Kabale University |
| issn | 2090-6838 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Psychiatry |
| spelling | doaj-art-ba0ac60fabfd4d548af912b0c685701e2025-02-03T01:30:21ZengWileyCase Reports in Psychiatry2090-68382024-01-01202410.1155/2024/8824770A Case of Phenibut Withdrawal Management and Detoxification Using Baclofen in the Outpatient SettingEmma DiFiore0Julie Pittman1Anne Burnett Marion School of MedicineAnne Burnett Marion School of MedicinePhenibut, a GABAB receptor agonist, has surged in popularity due to its nootropic and anxiolytic effects. Despite not being FDA approved, it is accessible online due to its marketing as a dietary supplement, leading to unregulated distribution. Increasing reports have highlighted the risks of addiction and severe withdrawal symptoms associated with phenibut use. This case report explores the management of phenibut withdrawal in an outpatient setting using a baclofen taper. The slow taper was complicated by various withdrawal symptoms, and the patient was ultimately stabilized on lorazepam, baclofen, gabapentin, and clonidine after 5-months time. This case is unique, as it also highlights challenges in tapering off baclofen following phenibut detoxification. The study underscores the need for further research on the pharmacological management of phenibut withdrawal, emphasizing the importance of raising awareness about phenibut’s dangers and associated clinical presentations.http://dx.doi.org/10.1155/2024/8824770 |
| spellingShingle | Emma DiFiore Julie Pittman A Case of Phenibut Withdrawal Management and Detoxification Using Baclofen in the Outpatient Setting Case Reports in Psychiatry |
| title | A Case of Phenibut Withdrawal Management and Detoxification Using Baclofen in the Outpatient Setting |
| title_full | A Case of Phenibut Withdrawal Management and Detoxification Using Baclofen in the Outpatient Setting |
| title_fullStr | A Case of Phenibut Withdrawal Management and Detoxification Using Baclofen in the Outpatient Setting |
| title_full_unstemmed | A Case of Phenibut Withdrawal Management and Detoxification Using Baclofen in the Outpatient Setting |
| title_short | A Case of Phenibut Withdrawal Management and Detoxification Using Baclofen in the Outpatient Setting |
| title_sort | case of phenibut withdrawal management and detoxification using baclofen in the outpatient setting |
| url | http://dx.doi.org/10.1155/2024/8824770 |
| work_keys_str_mv | AT emmadifiore acaseofphenibutwithdrawalmanagementanddetoxificationusingbaclofenintheoutpatientsetting AT juliepittman acaseofphenibutwithdrawalmanagementanddetoxificationusingbaclofenintheoutpatientsetting AT emmadifiore caseofphenibutwithdrawalmanagementanddetoxificationusingbaclofenintheoutpatientsetting AT juliepittman caseofphenibutwithdrawalmanagementanddetoxificationusingbaclofenintheoutpatientsetting |