A Case of Chronic Pancreatic Insufficiency Due to Valproic Acid in a Child
A 14-year-old child treated with valproic acid over several years for a seizure disorder developed abdominal pain with radiological evidence of acute pancreatitis. The association with valproic acid was not recognized, and the child continued to take the drug. The patient eventually develo...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2001-01-01
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| Series: | Canadian Journal of Gastroenterology |
| Online Access: | http://dx.doi.org/10.1155/2001/687087 |
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| _version_ | 1832545395401555968 |
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| author | Mary Anne Cooper Aubrey Groll |
| author_facet | Mary Anne Cooper Aubrey Groll |
| author_sort | Mary Anne Cooper |
| collection | DOAJ |
| description | A 14-year-old child treated with valproic acid over several years for a seizure disorder developed abdominal pain with radiological evidence of acute pancreatitis. The association with valproic acid was not recognized, and the child continued to take the drug. The patient eventually developed steatorrhea and weight loss that improved with pancreatic enzyme replacement. Radiological evaluation showed an atrophic pancreas. Without evidence of other etiological factors, valproic acid by itself appeared to be the cause of chronic pancreatitis with exocrine pancreatic insufficiency in this patient. |
| format | Article |
| id | doaj-art-b9f95e6a17a64d71a38ab06b11883edd |
| institution | Kabale University |
| issn | 0835-7900 |
| language | English |
| publishDate | 2001-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Gastroenterology |
| spelling | doaj-art-b9f95e6a17a64d71a38ab06b11883edd2025-02-03T07:26:05ZengWileyCanadian Journal of Gastroenterology0835-79002001-01-0115212713010.1155/2001/687087A Case of Chronic Pancreatic Insufficiency Due to Valproic Acid in a ChildMary Anne Cooper0Aubrey Groll11Sunnybrook and Womens College Health Sciences Centre, Sunnybrook Campus, University of Toronto, Toronto, CanadaHotel Dieu Hospital, Queen’s University, Kingston, Ontario, CanadaA 14-year-old child treated with valproic acid over several years for a seizure disorder developed abdominal pain with radiological evidence of acute pancreatitis. The association with valproic acid was not recognized, and the child continued to take the drug. The patient eventually developed steatorrhea and weight loss that improved with pancreatic enzyme replacement. Radiological evaluation showed an atrophic pancreas. Without evidence of other etiological factors, valproic acid by itself appeared to be the cause of chronic pancreatitis with exocrine pancreatic insufficiency in this patient.http://dx.doi.org/10.1155/2001/687087 |
| spellingShingle | Mary Anne Cooper Aubrey Groll A Case of Chronic Pancreatic Insufficiency Due to Valproic Acid in a Child Canadian Journal of Gastroenterology |
| title | A Case of Chronic Pancreatic Insufficiency Due to Valproic Acid in a Child |
| title_full | A Case of Chronic Pancreatic Insufficiency Due to Valproic Acid in a Child |
| title_fullStr | A Case of Chronic Pancreatic Insufficiency Due to Valproic Acid in a Child |
| title_full_unstemmed | A Case of Chronic Pancreatic Insufficiency Due to Valproic Acid in a Child |
| title_short | A Case of Chronic Pancreatic Insufficiency Due to Valproic Acid in a Child |
| title_sort | case of chronic pancreatic insufficiency due to valproic acid in a child |
| url | http://dx.doi.org/10.1155/2001/687087 |
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