The mediating role of inflammatory factors in the relationship between obesity and gallstone disease: evidence from the NHANES 2017–2020

The mediating role of inflammatory factors in the relationship between obesity and gallstone disease: evidence from the NHANES 2017–2020

Abstract Background Obesity is a well-known risk factor for gallstone disease, but the underlying mechanisms remain unclear. Recent studies suggest that inflammation may mediate the relationship between obesity and gallstones. This study, based on the 2017–2020 NHANES dataset, aims to explore this a...

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Bibliographic Details
Main Authors: Xu Zhen, Hou Yisen, Jiang Weirong, Li Zhiwen, Li Rui, Chen Wenhao, Meng Yong, Han Jianli
Format: Article
Language:English
Published: BMC 2025-07-01
Series:European Journal of Medical Research
Subjects:
Obesity
Gallstones
Inflammatory markers
National Health and Nutrition Examination Survey
Causal mediation analysis
Online Access:https://doi.org/10.1186/s40001-025-02915-7
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