Association between sex steroid hormones and α-klotho: Results from the NHANES 2013-2016 and Mendelian randomization study

Association between sex steroid hormones and α-klotho: Results from the NHANES 2013-2016 and Mendelian randomization study

Purpose: This study aimed to explore the association and causal links between sex steroid hormones and the anti-aging protein α-Klotho, extending to investigate the mediation effects of potential mediators. Methods: Based on data from the National Health and Nutrition Examination Survey (NHANES) 201...

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Bibliographic Details
Main Authors: Andong Guo, Pengcheng Chen, Jishuang Cao, Chenrui Wu, Sentai Ding
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Experimental Gerontology
Subjects:
α-Klotho
Sex steroid hormones
Mediation analysis
NHANES
Mendelian randomization
Online Access:http://www.sciencedirect.com/science/article/pii/S0531556525000270
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