Ras-MAPK pathway in patients with lupus nephritis

Ras-MAPK pathway in patients with lupus nephritis

Background Pathogenic mutations in genes encoding components of the Ras/mitogen-activated protein kinase (Ras-MAPK) pathway cause RASopathy. Here, we describe five unrelated patients with SLE carrying mutations associated with RASopathy and investigate the activity of the Ras-MAPK pathway.Methods Pa...

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Main Authors: Dandan Liang, Zhihong Liu, Haitao Zhang, Changming Zhang, Jiahui Zhang, Ying Jin, Qing Zhong, JingXian Yu, Yangyang Zhang, Xiaoman Jing, Xingjian Gao
Format: Article
Language:English
Published: BMJ Publishing Group 2025-03-01
Series:Lupus Science and Medicine
Online Access:https://lupus.bmj.com/content/12/1/e001345.full
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