Ultrasound Estimates of Visceral and Subcutaneous-Abdominal Adipose Tissues in Infancy
Other imaging techniques to quantify internal-abdominal adiposity (IA-AT) and subcutaneous-abdominal adiposity (SCA-AT) are frequently impractical in infants. The aim of this study was twofold: (a) to validate ultrasound (US) visceral and subcutaneous-abdominal depths in assessing IA-AT and SCA-AT f...
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Wiley
2013-01-01
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| Series: | Journal of Obesity |
| Online Access: | http://dx.doi.org/10.1155/2013/951954 |
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| author | Emanuella De Lucia Rolfe Neena Modi Sabita Uthaya Ieuan A. Hughes David B. Dunger Carlo Acerini Ronald P. Stolk Ken K. Ong |
| author_facet | Emanuella De Lucia Rolfe Neena Modi Sabita Uthaya Ieuan A. Hughes David B. Dunger Carlo Acerini Ronald P. Stolk Ken K. Ong |
| author_sort | Emanuella De Lucia Rolfe |
| collection | DOAJ |
| description | Other imaging techniques to quantify internal-abdominal adiposity (IA-AT) and subcutaneous-abdominal adiposity (SCA-AT) are frequently impractical in infants. The aim of this study was twofold: (a) to validate ultrasound (US) visceral and subcutaneous-abdominal depths in assessing IA-AT and SCA-AT from MRI as the reference method in infants and (b) to analyze the association between US abdominal adiposity and anthropometric measures at ages 3 months and 12 months. Twenty-two infants underwent MRI and US measures of abdominal adiposity. Abdominal US parameters and anthropometric variables were assessed in the Cambridge Baby Growth Study (CBGS), infants (23 girls) at age 3 months and infants (237 girls) at 12 months. US visceral and subcutaneous-abdominal depths correlated with MRI quantified IA-AT (, ) and SCA-AT (, ) volumes, respectively. In CBGS, mean US-visceral depths increased by 20
% between ages 3 and 12 months () and at both ages were lower in infants breast-fed at 3 months than in other infants. US-visceral depths at both 3 and 12 months were inversely related to skinfold thickness at birth ( and at 3 and 12 months, resp.; adjusted for current skinfold thickness). In contrast, US-subcutaneous-abdominal depth at 3 months was positively related to skinfold thickness at birth (). US measures can rank infants with higher or lower IA-AT and SCA-AT. Contrasting patterns of association with visceral and subcutaneous-abdominal adiposities indicate that they may be differentially regulated in infancy. |
| format | Article |
| id | doaj-art-b97a9b7cb101414eae1bf613a83ace50 |
| institution | Kabale University |
| issn | 2090-0708 2090-0716 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Obesity |
| spelling | doaj-art-b97a9b7cb101414eae1bf613a83ace502025-02-03T01:11:16ZengWileyJournal of Obesity2090-07082090-07162013-01-01201310.1155/2013/951954951954Ultrasound Estimates of Visceral and Subcutaneous-Abdominal Adipose Tissues in InfancyEmanuella De Lucia Rolfe0Neena Modi1Sabita Uthaya2Ieuan A. Hughes3David B. Dunger4Carlo Acerini5Ronald P. Stolk6Ken K. Ong7MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke’s Hospital, P.O. Box 285, Cambridge CB2 0QQ, UKSection of Neonatal Medicine, Department of Medicine Chelsea and Westminster Hospital Campus, Imperial College London, London SW10 9NH, UKSection of Neonatal Medicine, Department of Medicine Chelsea and Westminster Hospital Campus, Imperial College London, London SW10 9NH, UKDepartment of Paediatrics, University of Cambridge, Addenbrooke’s Hospital, P.O. Box 116, Cambridge CB2 0QQ, UKDepartment of Paediatrics, University of Cambridge, Addenbrooke’s Hospital, P.O. Box 116, Cambridge CB2 0QQ, UKDepartment of Paediatrics, University of Cambridge, Addenbrooke’s Hospital, P.O. Box 116, Cambridge CB2 0QQ, UKDepartment of Epidemiology, Groningen University, 9700 RB Groningen, The NetherlandsMRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke’s Hospital, P.O. Box 285, Cambridge CB2 0QQ, UKOther imaging techniques to quantify internal-abdominal adiposity (IA-AT) and subcutaneous-abdominal adiposity (SCA-AT) are frequently impractical in infants. The aim of this study was twofold: (a) to validate ultrasound (US) visceral and subcutaneous-abdominal depths in assessing IA-AT and SCA-AT from MRI as the reference method in infants and (b) to analyze the association between US abdominal adiposity and anthropometric measures at ages 3 months and 12 months. Twenty-two infants underwent MRI and US measures of abdominal adiposity. Abdominal US parameters and anthropometric variables were assessed in the Cambridge Baby Growth Study (CBGS), infants (23 girls) at age 3 months and infants (237 girls) at 12 months. US visceral and subcutaneous-abdominal depths correlated with MRI quantified IA-AT (, ) and SCA-AT (, ) volumes, respectively. In CBGS, mean US-visceral depths increased by 20 % between ages 3 and 12 months () and at both ages were lower in infants breast-fed at 3 months than in other infants. US-visceral depths at both 3 and 12 months were inversely related to skinfold thickness at birth ( and at 3 and 12 months, resp.; adjusted for current skinfold thickness). In contrast, US-subcutaneous-abdominal depth at 3 months was positively related to skinfold thickness at birth (). US measures can rank infants with higher or lower IA-AT and SCA-AT. Contrasting patterns of association with visceral and subcutaneous-abdominal adiposities indicate that they may be differentially regulated in infancy.http://dx.doi.org/10.1155/2013/951954 |
| spellingShingle | Emanuella De Lucia Rolfe Neena Modi Sabita Uthaya Ieuan A. Hughes David B. Dunger Carlo Acerini Ronald P. Stolk Ken K. Ong Ultrasound Estimates of Visceral and Subcutaneous-Abdominal Adipose Tissues in Infancy Journal of Obesity |
| title | Ultrasound Estimates of Visceral and Subcutaneous-Abdominal Adipose Tissues in Infancy |
| title_full | Ultrasound Estimates of Visceral and Subcutaneous-Abdominal Adipose Tissues in Infancy |
| title_fullStr | Ultrasound Estimates of Visceral and Subcutaneous-Abdominal Adipose Tissues in Infancy |
| title_full_unstemmed | Ultrasound Estimates of Visceral and Subcutaneous-Abdominal Adipose Tissues in Infancy |
| title_short | Ultrasound Estimates of Visceral and Subcutaneous-Abdominal Adipose Tissues in Infancy |
| title_sort | ultrasound estimates of visceral and subcutaneous abdominal adipose tissues in infancy |
| url | http://dx.doi.org/10.1155/2013/951954 |
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