Cross-reactive antibody against human coronavirus OC43 spike protein correlates with disease severity in COVID-19 patients: a retrospective study

Cross-reactive antibody against human coronavirus OC43 spike protein correlates with disease severity in COVID-19 patients: a retrospective study

Seasonal human coronaviruses (HCoVs) including HCoV-229E, -OC43, -NL63, and -HKU1 widely spread in global human populations. However, the relevance of humoral response against seasonal HCoVs to COVID-19 pathogenesis is elusive. In this study, we profiled the temporal changes of IgG antibody against...

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Bibliographic Details
Main Authors: Li Guo, Yeming Wang, Liang Kang, Yongfeng Hu, Linghang Wang, Jingchuan Zhong, Hong Chen, Lili Ren, Xiaoying Gu, Geng Wang, Conghui Wang, Xiaojing Dong, Chao Wu, Lianlian Han, Ying Wang, Guohui Fan, Xiaohui Zou, Haibo Li, Jiuyang Xu, Qi Jin, Bin Cao, Jianwei Wang
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Emerging Microbes and Infections
Subjects:
Cross-reactivity
antibody
HCoV-OC43
SARS-CoV-2
disease severity
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2021.1905488
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