The neutrophil extracellular trap-related gene FPR1 (formyl peptide receptor 1) as a potential prognostic and therapeutic target in osteosarcoma

The neutrophil extracellular trap-related gene FPR1 (formyl peptide receptor 1) as a potential prognostic and therapeutic target in osteosarcoma

Abstract Background Neutrophil extracellular trap (NET) has been implicated in cancer progression and metastasis. Nevertheless, the role of the NET-related gene, formyl peptide receptor 1 (FPR1), in osteosarcoma (OS) remains largely unexplored. This study aimed to investigate the prognostic signific...

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Bibliographic Details
Main Authors: Shihao Li, Qiong Yuan, Yuanyuan Zhang, Haiyang Zhang
Format: Article
Language:English
Published: BMC 2025-03-01
Series:BMC Musculoskeletal Disorders
Subjects:
Osteosarcoma
Neutrophil extracellular trap
Single cell RNA sequencing
Prognosis
Tumor microenvironment
FPR1
Online Access:https://doi.org/10.1186/s12891-024-08231-1
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