Primary Clear Cell Chondrosarcoma of the Spine: A Case Report of a Rare Entity and a Review of the Literature
Chondrosarcoma is the third most common primary malignant bone tumor after osteosarcoma and Ewing’s sarcoma. Clear cell chondrosarcoma is a rare subtype variant of chondrosarcoma, most commonly encountered in the proximal part of the femur or humerus. Vertebral involvement is exceedingly rare and sh...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Case Reports in Oncological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2012/693137 |
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| author | Nikolaos A. Paidakakos Aristides Rovlias Evaggelos Rokas Spyridon Theodoropoulos Patroklos Katafygiotis |
| author_facet | Nikolaos A. Paidakakos Aristides Rovlias Evaggelos Rokas Spyridon Theodoropoulos Patroklos Katafygiotis |
| author_sort | Nikolaos A. Paidakakos |
| collection | DOAJ |
| description | Chondrosarcoma is the third most common primary malignant bone tumor after osteosarcoma and Ewing’s sarcoma. Clear cell chondrosarcoma is a rare subtype variant of chondrosarcoma, most commonly encountered in the proximal part of the femur or humerus. Vertebral involvement is exceedingly rare and shows a predilection for the thoracic spine. We report the case of a woman with clear cell chondrosarcoma of the thoracic spine, which has been surgically excised, and review the pertinent literature (PubMed). Although it has a reasonably benign biological behavior, clear cell chondrosarcoma needs to be treated as a malignancy. The best treatment for spinal chondrosarcoma is surgery. It should be promptly and adequately resected. Gross-total resection should be the ultimate surgical goal. Radiation therapy should also be considered, especially in the case of subtotal resection or inoperable lesions. In conclusion, it is important to keep in mind this entity in the differential diagnosis of spinal tumors, in order to optimize treatment planning. With adequate treatment, local recurrence rates as low as 20% can be achieved. |
| format | Article |
| id | doaj-art-b95df16df9654d319c4cd98e3587155d |
| institution | Kabale University |
| issn | 2090-6706 2090-6714 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Oncological Medicine |
| spelling | doaj-art-b95df16df9654d319c4cd98e3587155d2025-02-03T01:25:53ZengWileyCase Reports in Oncological Medicine2090-67062090-67142012-01-01201210.1155/2012/693137693137Primary Clear Cell Chondrosarcoma of the Spine: A Case Report of a Rare Entity and a Review of the LiteratureNikolaos A. Paidakakos0Aristides Rovlias1Evaggelos Rokas2Spyridon Theodoropoulos3Patroklos Katafygiotis4Department of Neurosurgery, Asclepeion Voulas General Hospital, Vassileos Pavlou 1, Voula, 16673 Athens, GreeceDepartment of Neurosurgery, Asclepeion Voulas General Hospital, Vassileos Pavlou 1, Voula, 16673 Athens, GreeceDepartment of Neurosurgery, Asclepeion Voulas General Hospital, Vassileos Pavlou 1, Voula, 16673 Athens, GreeceDepartment of Neurosurgery, Asclepeion Voulas General Hospital, Vassileos Pavlou 1, Voula, 16673 Athens, GreeceDepartment of Pathology, Asclepeion Voulas General Hospital, Vassileos Pavlou 1, Voula, 16673 Athens, GreeceChondrosarcoma is the third most common primary malignant bone tumor after osteosarcoma and Ewing’s sarcoma. Clear cell chondrosarcoma is a rare subtype variant of chondrosarcoma, most commonly encountered in the proximal part of the femur or humerus. Vertebral involvement is exceedingly rare and shows a predilection for the thoracic spine. We report the case of a woman with clear cell chondrosarcoma of the thoracic spine, which has been surgically excised, and review the pertinent literature (PubMed). Although it has a reasonably benign biological behavior, clear cell chondrosarcoma needs to be treated as a malignancy. The best treatment for spinal chondrosarcoma is surgery. It should be promptly and adequately resected. Gross-total resection should be the ultimate surgical goal. Radiation therapy should also be considered, especially in the case of subtotal resection or inoperable lesions. In conclusion, it is important to keep in mind this entity in the differential diagnosis of spinal tumors, in order to optimize treatment planning. With adequate treatment, local recurrence rates as low as 20% can be achieved.http://dx.doi.org/10.1155/2012/693137 |
| spellingShingle | Nikolaos A. Paidakakos Aristides Rovlias Evaggelos Rokas Spyridon Theodoropoulos Patroklos Katafygiotis Primary Clear Cell Chondrosarcoma of the Spine: A Case Report of a Rare Entity and a Review of the Literature Case Reports in Oncological Medicine |
| title | Primary Clear Cell Chondrosarcoma of the Spine: A Case Report of a Rare Entity and a Review of the Literature |
| title_full | Primary Clear Cell Chondrosarcoma of the Spine: A Case Report of a Rare Entity and a Review of the Literature |
| title_fullStr | Primary Clear Cell Chondrosarcoma of the Spine: A Case Report of a Rare Entity and a Review of the Literature |
| title_full_unstemmed | Primary Clear Cell Chondrosarcoma of the Spine: A Case Report of a Rare Entity and a Review of the Literature |
| title_short | Primary Clear Cell Chondrosarcoma of the Spine: A Case Report of a Rare Entity and a Review of the Literature |
| title_sort | primary clear cell chondrosarcoma of the spine a case report of a rare entity and a review of the literature |
| url | http://dx.doi.org/10.1155/2012/693137 |
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