An Analysis of 3-Year Outcomes Following Canaloplasty for the Treatment of Open-Angle Glaucoma

Purpose. To report 3-year results investigating the safety and efficacy of canaloplasty for open-angle glaucoma. Setting. University of Oklahoma, Dean McGee Eye Institute, Oklahoma, United States of America. Design. Nonrandomized single-center retrospective chart review. Methods. Adult open-angle gl...

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Main Authors: Mahmoud A. Khaimi, Justin D. Dvorak, Kai Ding
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Journal of Ophthalmology
Online Access:http://dx.doi.org/10.1155/2017/2904272
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author Mahmoud A. Khaimi
Justin D. Dvorak
Kai Ding
author_facet Mahmoud A. Khaimi
Justin D. Dvorak
Kai Ding
author_sort Mahmoud A. Khaimi
collection DOAJ
description Purpose. To report 3-year results investigating the safety and efficacy of canaloplasty for open-angle glaucoma. Setting. University of Oklahoma, Dean McGee Eye Institute, Oklahoma, United States of America. Design. Nonrandomized single-center retrospective chart review. Methods. Adult open-angle glaucoma eyes underwent canaloplasty or combined cataract-canaloplasty surgery. A tensioning suture was placed into Schlemm’s canal in all eyes. Primary endpoints included the mean IOP and mean number of glaucoma medications at each follow-up visit. Secondary endpoints included visual acuity and surgical/postsurgical complications. Results. The study cohort included 277 eyes (mean age, 72.8 years). Overall, the mean baseline IOP of 19.7 mmHg was reduced to 14.3 mmHg,14.0 mmHg, and 15.2 mmHg at 1, 2, and 3 years, respectively (p<0.001). The average medicine use was reduced from 2.1 preoperatively to 0.4 at 12 months, and 0.5 and 0.6 at two and three years, respectively (p<0.001). The frequency of surgical and postsurgical complications was low with no serious adverse events recorded. Conclusion. Canaloplasty was safe and effective in achieving long-term IOP reductions and reduced dependence on antiglaucoma medications.
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spelling doaj-art-b9054bc7abe642fcbec8cb0a3092b9912025-02-03T01:11:53ZengWileyJournal of Ophthalmology2090-004X2090-00582017-01-01201710.1155/2017/29042722904272An Analysis of 3-Year Outcomes Following Canaloplasty for the Treatment of Open-Angle GlaucomaMahmoud A. Khaimi0Justin D. Dvorak1Kai Ding2Dean McGee Eye Institute, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USADepartment of Biostatistics and Epidemiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USADepartment of Biostatistics and Epidemiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USAPurpose. To report 3-year results investigating the safety and efficacy of canaloplasty for open-angle glaucoma. Setting. University of Oklahoma, Dean McGee Eye Institute, Oklahoma, United States of America. Design. Nonrandomized single-center retrospective chart review. Methods. Adult open-angle glaucoma eyes underwent canaloplasty or combined cataract-canaloplasty surgery. A tensioning suture was placed into Schlemm’s canal in all eyes. Primary endpoints included the mean IOP and mean number of glaucoma medications at each follow-up visit. Secondary endpoints included visual acuity and surgical/postsurgical complications. Results. The study cohort included 277 eyes (mean age, 72.8 years). Overall, the mean baseline IOP of 19.7 mmHg was reduced to 14.3 mmHg,14.0 mmHg, and 15.2 mmHg at 1, 2, and 3 years, respectively (p<0.001). The average medicine use was reduced from 2.1 preoperatively to 0.4 at 12 months, and 0.5 and 0.6 at two and three years, respectively (p<0.001). The frequency of surgical and postsurgical complications was low with no serious adverse events recorded. Conclusion. Canaloplasty was safe and effective in achieving long-term IOP reductions and reduced dependence on antiglaucoma medications.http://dx.doi.org/10.1155/2017/2904272
spellingShingle Mahmoud A. Khaimi
Justin D. Dvorak
Kai Ding
An Analysis of 3-Year Outcomes Following Canaloplasty for the Treatment of Open-Angle Glaucoma
Journal of Ophthalmology
title An Analysis of 3-Year Outcomes Following Canaloplasty for the Treatment of Open-Angle Glaucoma
title_full An Analysis of 3-Year Outcomes Following Canaloplasty for the Treatment of Open-Angle Glaucoma
title_fullStr An Analysis of 3-Year Outcomes Following Canaloplasty for the Treatment of Open-Angle Glaucoma
title_full_unstemmed An Analysis of 3-Year Outcomes Following Canaloplasty for the Treatment of Open-Angle Glaucoma
title_short An Analysis of 3-Year Outcomes Following Canaloplasty for the Treatment of Open-Angle Glaucoma
title_sort analysis of 3 year outcomes following canaloplasty for the treatment of open angle glaucoma
url http://dx.doi.org/10.1155/2017/2904272
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