Effect of Butein, a Plant Polyphenol, on Apoptosis and Necroptosis of Prostate Cancer Cells in 2D and 3D Cultures

Effect of Butein, a Plant Polyphenol, on Apoptosis and Necroptosis of Prostate Cancer Cells in 2D and 3D Cultures

Butein (3,4,2′,4′-tetrahydroxycalone) is a chalcone derivative and plant polyphenol extracted from <i>Rhus verniciflua Stokes</i>. Butein has an open C-ring structure and a variety of biological activities. Molecular mechanisms by which butein could affect cell viability, ROS levels, mit...

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Bibliographic Details
Main Authors: Yeji Lee, Changyeol Lee, Sang-Han Lee, Yoon-Jin Lee
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Life
Subjects:
butein
apoptosis
necroptosis
prostate cancer cells
DNA damage
Online Access:https://www.mdpi.com/2075-1729/15/6/836
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