Purine-rich element binding protein alpha: a DNA/RNA binding protein with multiple roles in cancers

Purine-rich element binding protein alpha: a DNA/RNA binding protein with multiple roles in cancers

Abstract Proteins that bind to DNA/RNA are typically evolutionarily conserved with multiple regulatory functions in transcription initiation, mRNA translation, stability of RNAs, and RNA splicing. Therefore, dysregulation of DNA/RNA binding proteins such as purine-rich element binding protein alpha...

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Bibliographic Details
Main Authors: Shiyi Yu, Chengyang Jiang, Yawen Yang, Fei Cheng, Fangchen Liu, Chang Liu, Xue Gong
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Molecular Medicine
Subjects:
DNA/RNA binding protein
PURα
Cancer
Biomarker
Online Access:https://doi.org/10.1186/s10020-025-01087-8
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