Umbilical Cord Tissue-Derived Cells as Therapeutic Agents
Although the characteristics of SC, including UC-derived cells, are a dramatically discussed issue, this review will focus particularly on some controversial issues regarding clinical utility of cells isolated from UC tissue. UC-derived cells have several advantages compared to other types and sourc...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2015-01-01
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| Series: | Stem Cells International |
| Online Access: | http://dx.doi.org/10.1155/2015/150609 |
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| _version_ | 1832562836919812096 |
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| author | Olga Maslova Miroslav Novak Peter Kruzliak |
| author_facet | Olga Maslova Miroslav Novak Peter Kruzliak |
| author_sort | Olga Maslova |
| collection | DOAJ |
| description | Although the characteristics of SC, including UC-derived cells, are a dramatically discussed issue, this review will focus particularly on some controversial issues regarding clinical utility of cells isolated from UC tissue. UC-derived cells have several advantages compared to other types and sources of stem cells. The impact of UC topography on cell characteristics is briefly discussed. The necessity to adapt existing methods of cell isolation and culturing to GMP conditions is mentioned, as well as possible cryopreservation of this material. Light is shed on some future perspectives for UC-derived cells. |
| format | Article |
| id | doaj-art-b89a0db805834e93aa8122ec66a43460 |
| institution | Kabale University |
| issn | 1687-966X 1687-9678 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Stem Cells International |
| spelling | doaj-art-b89a0db805834e93aa8122ec66a434602025-02-03T01:21:40ZengWileyStem Cells International1687-966X1687-96782015-01-01201510.1155/2015/150609150609Umbilical Cord Tissue-Derived Cells as Therapeutic AgentsOlga Maslova0Miroslav Novak1Peter Kruzliak2National Taras Shevchenko University of Kyiv, Kyiv, UkraineInternational Clinical Research Center, St. Anne’s University Hospital and Masaryk University, Pekarska 53, 656 91 Brno, Czech RepublicInternational Clinical Research Center, St. Anne’s University Hospital and Masaryk University, Pekarska 53, 656 91 Brno, Czech RepublicAlthough the characteristics of SC, including UC-derived cells, are a dramatically discussed issue, this review will focus particularly on some controversial issues regarding clinical utility of cells isolated from UC tissue. UC-derived cells have several advantages compared to other types and sources of stem cells. The impact of UC topography on cell characteristics is briefly discussed. The necessity to adapt existing methods of cell isolation and culturing to GMP conditions is mentioned, as well as possible cryopreservation of this material. Light is shed on some future perspectives for UC-derived cells.http://dx.doi.org/10.1155/2015/150609 |
| spellingShingle | Olga Maslova Miroslav Novak Peter Kruzliak Umbilical Cord Tissue-Derived Cells as Therapeutic Agents Stem Cells International |
| title | Umbilical Cord Tissue-Derived Cells as Therapeutic Agents |
| title_full | Umbilical Cord Tissue-Derived Cells as Therapeutic Agents |
| title_fullStr | Umbilical Cord Tissue-Derived Cells as Therapeutic Agents |
| title_full_unstemmed | Umbilical Cord Tissue-Derived Cells as Therapeutic Agents |
| title_short | Umbilical Cord Tissue-Derived Cells as Therapeutic Agents |
| title_sort | umbilical cord tissue derived cells as therapeutic agents |
| url | http://dx.doi.org/10.1155/2015/150609 |
| work_keys_str_mv | AT olgamaslova umbilicalcordtissuederivedcellsastherapeuticagents AT miroslavnovak umbilicalcordtissuederivedcellsastherapeuticagents AT peterkruzliak umbilicalcordtissuederivedcellsastherapeuticagents |