Insights into Novel Arylazopyrazolo[1,5‑a]pyrimidines as Promising MurA Inhibitors and Antibiofilm Candidates: Design, Synthesis, Antimicrobial Evaluation, and Molecular Docking
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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American Chemical Society
2025-01-01
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| Series: | ACS Omega |
| Online Access: | https://doi.org/10.1021/acsomega.4c10286 |
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| _version_ | 1832541243885748224 |
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| author | Omkulthom Al kamaly Amel S. Younes Mona H. Ibrahim Marwa F. Harras Aisha A. Alsfouk Rehab Sabour |
| author_facet | Omkulthom Al kamaly Amel S. Younes Mona H. Ibrahim Marwa F. Harras Aisha A. Alsfouk Rehab Sabour |
| author_sort | Omkulthom Al kamaly |
| collection | DOAJ |
| format | Article |
| id | doaj-art-b8939df5d1244d98a1784c2a061b2a2e |
| institution | Kabale University |
| issn | 2470-1343 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | American Chemical Society |
| record_format | Article |
| series | ACS Omega |
| spelling | doaj-art-b8939df5d1244d98a1784c2a061b2a2e2025-02-04T09:12:47ZengAmerican Chemical SocietyACS Omega2470-13432025-01-011044044405610.1021/acsomega.4c10286Insights into Novel Arylazopyrazolo[1,5‑a]pyrimidines as Promising MurA Inhibitors and Antibiofilm Candidates: Design, Synthesis, Antimicrobial Evaluation, and Molecular DockingOmkulthom Al kamaly0Amel S. Younes1Mona H. Ibrahim2Marwa F. Harras3Aisha A. Alsfouk4Rehab Sabour5Department of Pharmaceutical Sciences, College of Pharmacy, Princess Nourah bint Abdulrahman University, Riyadh, Saudi ArabiaDepartment of Pharmaceutical Medicinal Chemistry and Drug Design, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo, EgyptDepartment of Pharmaceutical Medicinal Chemistry and Drug Design, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo, EgyptDepartment of Pharmaceutical Medicinal Chemistry and Drug Design, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo, EgyptDepartment of Pharmaceutical Sciences, College of Pharmacy, Princess Nourah bint Abdulrahman University, Riyadh, Saudi ArabiaDepartment of Pharmaceutical Medicinal Chemistry and Drug Design, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo, Egypthttps://doi.org/10.1021/acsomega.4c10286 |
| spellingShingle | Omkulthom Al kamaly Amel S. Younes Mona H. Ibrahim Marwa F. Harras Aisha A. Alsfouk Rehab Sabour Insights into Novel Arylazopyrazolo[1,5‑a]pyrimidines as Promising MurA Inhibitors and Antibiofilm Candidates: Design, Synthesis, Antimicrobial Evaluation, and Molecular Docking ACS Omega |
| title | Insights into Novel Arylazopyrazolo[1,5‑a]pyrimidines as Promising MurA Inhibitors and Antibiofilm Candidates: Design, Synthesis, Antimicrobial Evaluation, and Molecular Docking |
| title_full | Insights into Novel Arylazopyrazolo[1,5‑a]pyrimidines as Promising MurA Inhibitors and Antibiofilm Candidates: Design, Synthesis, Antimicrobial Evaluation, and Molecular Docking |
| title_fullStr | Insights into Novel Arylazopyrazolo[1,5‑a]pyrimidines as Promising MurA Inhibitors and Antibiofilm Candidates: Design, Synthesis, Antimicrobial Evaluation, and Molecular Docking |
| title_full_unstemmed | Insights into Novel Arylazopyrazolo[1,5‑a]pyrimidines as Promising MurA Inhibitors and Antibiofilm Candidates: Design, Synthesis, Antimicrobial Evaluation, and Molecular Docking |
| title_short | Insights into Novel Arylazopyrazolo[1,5‑a]pyrimidines as Promising MurA Inhibitors and Antibiofilm Candidates: Design, Synthesis, Antimicrobial Evaluation, and Molecular Docking |
| title_sort | insights into novel arylazopyrazolo 1 5 a pyrimidines as promising mura inhibitors and antibiofilm candidates design synthesis antimicrobial evaluation and molecular docking |
| url | https://doi.org/10.1021/acsomega.4c10286 |
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