METTL3/miR-192-5p/SCD1 Axis Regulates Lipid Metabolism to Affect T Cell Differentiation in Asthma

Conclusion: These results suggest that METTL3/miR-192-5p/SCD1 axis regulates lipid metabolism and affects T cell differentiation, thus affecting asthma progression. This study may provide novel insights into the pathogenesis of asthma and a new treatment strategy.

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Main Authors: Zhengrong Chen, Dingwei Yan, Suyu Guo, Yiyi Song, Xinxing Zhang, Wenjing Gu, Heting Dong, Li Huang
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/mi/4955849
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author Zhengrong Chen
Dingwei Yan
Suyu Guo
Yiyi Song
Xinxing Zhang
Wenjing Gu
Heting Dong
Li Huang
author_facet Zhengrong Chen
Dingwei Yan
Suyu Guo
Yiyi Song
Xinxing Zhang
Wenjing Gu
Heting Dong
Li Huang
author_sort Zhengrong Chen
collection DOAJ
description Conclusion: These results suggest that METTL3/miR-192-5p/SCD1 axis regulates lipid metabolism and affects T cell differentiation, thus affecting asthma progression. This study may provide novel insights into the pathogenesis of asthma and a new treatment strategy.
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institution Kabale University
issn 1466-1861
language English
publishDate 2025-01-01
publisher Wiley
record_format Article
series Mediators of Inflammation
spelling doaj-art-b88cdfc2e3494439a7b9fb637d5d296a2025-01-27T00:00:01ZengWileyMediators of Inflammation1466-18612025-01-01202510.1155/mi/4955849METTL3/miR-192-5p/SCD1 Axis Regulates Lipid Metabolism to Affect T Cell Differentiation in AsthmaZhengrong Chen0Dingwei Yan1Suyu Guo2Yiyi Song3Xinxing Zhang4Wenjing Gu5Heting Dong6Li Huang7Department of Pediatric PulmonologyDepartment of Pediatric PulmonologyDepartment of Pediatric PulmonologySuzhou Medical CollegeDepartment of Pediatric PulmonologyDepartment of Pediatric PulmonologyDepartment of Pediatric PulmonologyDepartment of Pediatric PulmonologyConclusion: These results suggest that METTL3/miR-192-5p/SCD1 axis regulates lipid metabolism and affects T cell differentiation, thus affecting asthma progression. This study may provide novel insights into the pathogenesis of asthma and a new treatment strategy.http://dx.doi.org/10.1155/mi/4955849
spellingShingle Zhengrong Chen
Dingwei Yan
Suyu Guo
Yiyi Song
Xinxing Zhang
Wenjing Gu
Heting Dong
Li Huang
METTL3/miR-192-5p/SCD1 Axis Regulates Lipid Metabolism to Affect T Cell Differentiation in Asthma
Mediators of Inflammation
title METTL3/miR-192-5p/SCD1 Axis Regulates Lipid Metabolism to Affect T Cell Differentiation in Asthma
title_full METTL3/miR-192-5p/SCD1 Axis Regulates Lipid Metabolism to Affect T Cell Differentiation in Asthma
title_fullStr METTL3/miR-192-5p/SCD1 Axis Regulates Lipid Metabolism to Affect T Cell Differentiation in Asthma
title_full_unstemmed METTL3/miR-192-5p/SCD1 Axis Regulates Lipid Metabolism to Affect T Cell Differentiation in Asthma
title_short METTL3/miR-192-5p/SCD1 Axis Regulates Lipid Metabolism to Affect T Cell Differentiation in Asthma
title_sort mettl3 mir 192 5p scd1 axis regulates lipid metabolism to affect t cell differentiation in asthma
url http://dx.doi.org/10.1155/mi/4955849
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