Mini Review of Biochemical Basis, Diagnosis and Management of Crush Syndrome
Crush syndrome (CS) is a metabolic disorder whose victims are individuals suffered from natural disasters such as earthquake or man-made conflicts. CS complications include acute kidney injury and cardiac arrhythmia that collectively end with death if untreated immediately. These complications are...
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Format: | Article |
Language: | English |
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Vilnius University Press
2023-10-01
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Series: | Acta Medica Lituanica |
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Online Access: | https://www.journals.vu.lt/AML/article/view/31674 |
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author | Abdulhalim Hamlah Abd Alraouf Tarabishy Haitham Al-Madhagi |
author_facet | Abdulhalim Hamlah Abd Alraouf Tarabishy Haitham Al-Madhagi |
author_sort | Abdulhalim Hamlah |
collection | DOAJ |
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Crush syndrome (CS) is a metabolic disorder whose victims are individuals suffered from natural disasters such as earthquake or man-made conflicts. CS complications include acute kidney injury and cardiac arrhythmia that collectively end with death if untreated immediately. These complications are accounted for the liberation of damaged muscle tissues contents, primarily myoglobin and potassium. The present mini review discusses the biochemical basis of the development of CS. In addition, diagnosis and management and the application of novel experimental therapeutics of CS are also highlighted.
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format | Article |
id | doaj-art-b8725b78d36f46469351218d1d130f3d |
institution | Kabale University |
issn | 1392-0138 2029-4174 |
language | English |
publishDate | 2023-10-01 |
publisher | Vilnius University Press |
record_format | Article |
series | Acta Medica Lituanica |
spelling | doaj-art-b8725b78d36f46469351218d1d130f3d2025-01-20T18:08:08ZengVilnius University PressActa Medica Lituanica1392-01382029-41742023-10-0130210.15388/Amed.2023.30.2.5Mini Review of Biochemical Basis, Diagnosis and Management of Crush SyndromeAbdulhalim Hamlah0Abd Alraouf Tarabishy1Haitham Al-Madhagi2https://orcid.org/0000-0002-3850-244XAleppo University, SyriaAleppo University, SyriaDhamar University, Yemen Crush syndrome (CS) is a metabolic disorder whose victims are individuals suffered from natural disasters such as earthquake or man-made conflicts. CS complications include acute kidney injury and cardiac arrhythmia that collectively end with death if untreated immediately. These complications are accounted for the liberation of damaged muscle tissues contents, primarily myoglobin and potassium. The present mini review discusses the biochemical basis of the development of CS. In addition, diagnosis and management and the application of novel experimental therapeutics of CS are also highlighted. https://www.journals.vu.lt/AML/article/view/31674Crush syndromerhabdomyolysisacute kidney injuryarrhythmiamyoglobin |
spellingShingle | Abdulhalim Hamlah Abd Alraouf Tarabishy Haitham Al-Madhagi Mini Review of Biochemical Basis, Diagnosis and Management of Crush Syndrome Acta Medica Lituanica Crush syndrome rhabdomyolysis acute kidney injury arrhythmia myoglobin |
title | Mini Review of Biochemical Basis, Diagnosis and Management of Crush Syndrome |
title_full | Mini Review of Biochemical Basis, Diagnosis and Management of Crush Syndrome |
title_fullStr | Mini Review of Biochemical Basis, Diagnosis and Management of Crush Syndrome |
title_full_unstemmed | Mini Review of Biochemical Basis, Diagnosis and Management of Crush Syndrome |
title_short | Mini Review of Biochemical Basis, Diagnosis and Management of Crush Syndrome |
title_sort | mini review of biochemical basis diagnosis and management of crush syndrome |
topic | Crush syndrome rhabdomyolysis acute kidney injury arrhythmia myoglobin |
url | https://www.journals.vu.lt/AML/article/view/31674 |
work_keys_str_mv | AT abdulhalimhamlah minireviewofbiochemicalbasisdiagnosisandmanagementofcrushsyndrome AT abdalraouftarabishy minireviewofbiochemicalbasisdiagnosisandmanagementofcrushsyndrome AT haithamalmadhagi minireviewofbiochemicalbasisdiagnosisandmanagementofcrushsyndrome |