Mini Review of Biochemical Basis, Diagnosis and Management of Crush Syndrome

Crush syndrome (CS) is a metabolic disorder whose victims are individuals suffered from natural disasters such as earthquake or man-made conflicts. CS complications include acute kidney injury and cardiac arrhythmia that collectively end with death if untreated immediately. These complications are...

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Main Authors: Abdulhalim Hamlah, Abd Alraouf Tarabishy, Haitham Al-Madhagi
Format: Article
Language:English
Published: Vilnius University Press 2023-10-01
Series:Acta Medica Lituanica
Subjects:
Online Access:https://www.journals.vu.lt/AML/article/view/31674
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author Abdulhalim Hamlah
Abd Alraouf Tarabishy
Haitham Al-Madhagi
author_facet Abdulhalim Hamlah
Abd Alraouf Tarabishy
Haitham Al-Madhagi
author_sort Abdulhalim Hamlah
collection DOAJ
description Crush syndrome (CS) is a metabolic disorder whose victims are individuals suffered from natural disasters such as earthquake or man-made conflicts. CS complications include acute kidney injury and cardiac arrhythmia that collectively end with death if untreated immediately. These complications are accounted for the liberation of damaged muscle tissues contents, primarily myoglobin and potassium. The present mini review discusses the biochemical basis of the development of CS. In addition, diagnosis and management and the application of novel experimental therapeutics of CS are also highlighted.
format Article
id doaj-art-b8725b78d36f46469351218d1d130f3d
institution Kabale University
issn 1392-0138
2029-4174
language English
publishDate 2023-10-01
publisher Vilnius University Press
record_format Article
series Acta Medica Lituanica
spelling doaj-art-b8725b78d36f46469351218d1d130f3d2025-01-20T18:08:08ZengVilnius University PressActa Medica Lituanica1392-01382029-41742023-10-0130210.15388/Amed.2023.30.2.5Mini Review of Biochemical Basis, Diagnosis and Management of Crush SyndromeAbdulhalim Hamlah0Abd Alraouf Tarabishy1Haitham Al-Madhagi2https://orcid.org/0000-0002-3850-244XAleppo University, SyriaAleppo University, SyriaDhamar University, Yemen Crush syndrome (CS) is a metabolic disorder whose victims are individuals suffered from natural disasters such as earthquake or man-made conflicts. CS complications include acute kidney injury and cardiac arrhythmia that collectively end with death if untreated immediately. These complications are accounted for the liberation of damaged muscle tissues contents, primarily myoglobin and potassium. The present mini review discusses the biochemical basis of the development of CS. In addition, diagnosis and management and the application of novel experimental therapeutics of CS are also highlighted. https://www.journals.vu.lt/AML/article/view/31674Crush syndromerhabdomyolysisacute kidney injuryarrhythmiamyoglobin
spellingShingle Abdulhalim Hamlah
Abd Alraouf Tarabishy
Haitham Al-Madhagi
Mini Review of Biochemical Basis, Diagnosis and Management of Crush Syndrome
Acta Medica Lituanica
Crush syndrome
rhabdomyolysis
acute kidney injury
arrhythmia
myoglobin
title Mini Review of Biochemical Basis, Diagnosis and Management of Crush Syndrome
title_full Mini Review of Biochemical Basis, Diagnosis and Management of Crush Syndrome
title_fullStr Mini Review of Biochemical Basis, Diagnosis and Management of Crush Syndrome
title_full_unstemmed Mini Review of Biochemical Basis, Diagnosis and Management of Crush Syndrome
title_short Mini Review of Biochemical Basis, Diagnosis and Management of Crush Syndrome
title_sort mini review of biochemical basis diagnosis and management of crush syndrome
topic Crush syndrome
rhabdomyolysis
acute kidney injury
arrhythmia
myoglobin
url https://www.journals.vu.lt/AML/article/view/31674
work_keys_str_mv AT abdulhalimhamlah minireviewofbiochemicalbasisdiagnosisandmanagementofcrushsyndrome
AT abdalraouftarabishy minireviewofbiochemicalbasisdiagnosisandmanagementofcrushsyndrome
AT haithamalmadhagi minireviewofbiochemicalbasisdiagnosisandmanagementofcrushsyndrome