Rheological monitoring of tau protein polymerisation with acoustic waves sensor
Among acoustic waves sensors, the thickness shear mode resonator presents high sensitivity for the measurement of liquid viscoelastic properties, enabling the monitoring of the shear moduli, G′ G″, by using a suitable physical model. The development of an instrumental system for detecting the tau pr...
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| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2017-03-01
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| Series: | Electronics Letters |
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| Online Access: | https://doi.org/10.1049/el.2016.3400 |
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| _version_ | 1832096697689309184 |
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| author | P. Didier F. Razan E. Caplain M. Michiel C. Delamarche C. Nogues J.Y. Le Huerou S. Serfaty P. Larzabal |
| author_facet | P. Didier F. Razan E. Caplain M. Michiel C. Delamarche C. Nogues J.Y. Le Huerou S. Serfaty P. Larzabal |
| author_sort | P. Didier |
| collection | DOAJ |
| description | Among acoustic waves sensors, the thickness shear mode resonator presents high sensitivity for the measurement of liquid viscoelastic properties, enabling the monitoring of the shear moduli, G′ G″, by using a suitable physical model. The development of an instrumental system for detecting the tau protein involved in Alzheimer's disease is proposed which will aid in understanding the mechanisms of this disease. The tau protein is present in complex products such as blood and cerebrospinal fluid. The experimental results show that the acoustic wave system allows to differentiate between tau protein solutions with different states of polymerisation. |
| format | Article |
| id | doaj-art-b86f8d6259c84794a628e580b2e35d17 |
| institution | Kabale University |
| issn | 0013-5194 1350-911X |
| language | English |
| publishDate | 2017-03-01 |
| publisher | Wiley |
| record_format | Article |
| series | Electronics Letters |
| spelling | doaj-art-b86f8d6259c84794a628e580b2e35d172025-02-05T12:30:42ZengWileyElectronics Letters0013-51941350-911X2017-03-0153529830010.1049/el.2016.3400Rheological monitoring of tau protein polymerisation with acoustic waves sensorP. Didier0F. Razan1E. Caplain2M. Michiel3C. Delamarche4C. Nogues5J.Y. Le Huerou6S. Serfaty7P. Larzabal8SATIEUMR CNRS 8029, ENS Cachan61 Avenue du Président Wilson94235CachanFranceSATIEUMR CNRS 8029, ENS Cachan61 Avenue du Président Wilson94235CachanFranceSATIEUMR CNRS 8029, ENS Cachan61 Avenue du Président Wilson94235CachanFranceSATIEUMR CNRS 8029, ENS Cachan61 Avenue du Président Wilson94235CachanFranceIGDR, UMR CNRS 6290, Campus de BeaulieuUniversite de Rennes 1Bât. 1335042RennesFranceLBPA, UMR CNRS 8113, ENS CachanEcole Normale Superieure de Cachan61 Avenue du Président Wilson94235CachanFranceSATIEUMR CNRS 8029, ENS Cachan61 Avenue du Président Wilson94235CachanFranceSATIEUMR CNRS 8029, ENS Cachan61 Avenue du Président Wilson94235CachanFranceSATIEUMR CNRS 8029, ENS Cachan61 Avenue du Président Wilson94235CachanFranceAmong acoustic waves sensors, the thickness shear mode resonator presents high sensitivity for the measurement of liquid viscoelastic properties, enabling the monitoring of the shear moduli, G′ G″, by using a suitable physical model. The development of an instrumental system for detecting the tau protein involved in Alzheimer's disease is proposed which will aid in understanding the mechanisms of this disease. The tau protein is present in complex products such as blood and cerebrospinal fluid. The experimental results show that the acoustic wave system allows to differentiate between tau protein solutions with different states of polymerisation.https://doi.org/10.1049/el.2016.3400acoustic wave sensortau protein polymerisationrheological monitoringthickness shear mode resonatorshear moduliAlzheimer's disease |
| spellingShingle | P. Didier F. Razan E. Caplain M. Michiel C. Delamarche C. Nogues J.Y. Le Huerou S. Serfaty P. Larzabal Rheological monitoring of tau protein polymerisation with acoustic waves sensor Electronics Letters acoustic wave sensor tau protein polymerisation rheological monitoring thickness shear mode resonator shear moduli Alzheimer's disease |
| title | Rheological monitoring of tau protein polymerisation with acoustic waves sensor |
| title_full | Rheological monitoring of tau protein polymerisation with acoustic waves sensor |
| title_fullStr | Rheological monitoring of tau protein polymerisation with acoustic waves sensor |
| title_full_unstemmed | Rheological monitoring of tau protein polymerisation with acoustic waves sensor |
| title_short | Rheological monitoring of tau protein polymerisation with acoustic waves sensor |
| title_sort | rheological monitoring of tau protein polymerisation with acoustic waves sensor |
| topic | acoustic wave sensor tau protein polymerisation rheological monitoring thickness shear mode resonator shear moduli Alzheimer's disease |
| url | https://doi.org/10.1049/el.2016.3400 |
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