Azo Dyes and the Microbial World: Synthesis, Breakdown, and Bioactivity
This review discusses natural and synthetic azo compounds found in bacteria, fungal endophytes, fungi, plants, and invertebrates. More than 100 of these compounds have demonstrated significant pharmacological activity, including antitumor, antimicrobial, and antibacterial effects. Using mathematical...
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| Format: | Article |
| Language: | English |
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MDPI AG
2025-05-01
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| Series: | Microbiology Research |
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| Online Access: | https://www.mdpi.com/2036-7481/16/5/100 |
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| _version_ | 1849711880767012864 |
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| author | Valery M. Dembitsky Alexander O. Terent’ev |
| author_facet | Valery M. Dembitsky Alexander O. Terent’ev |
| author_sort | Valery M. Dembitsky |
| collection | DOAJ |
| description | This review discusses natural and synthetic azo compounds found in bacteria, fungal endophytes, fungi, plants, and invertebrates. More than 100 of these compounds have demonstrated significant pharmacological activity, including antitumor, antimicrobial, and antibacterial effects. Using mathematical algorithms and the PASS program, researchers predict new potential applications based on their structure–activity relationships. This review emphasizes the importance of natural azo compounds as promising drug prototypes and key players in drug discovery. It also explores the synthesis and degradation of azo dyes and their potential uses in medicine, food, cosmetics, and related fields. Additionally, the role of microorganisms in producing natural azo compounds and their synthetic counterparts is examined, showcasing their potential in drug development and human health advancements. |
| format | Article |
| id | doaj-art-b86bb6cd903549ce8eacf511fc478eb6 |
| institution | DOAJ |
| issn | 2036-7481 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Microbiology Research |
| spelling | doaj-art-b86bb6cd903549ce8eacf511fc478eb62025-08-20T03:14:29ZengMDPI AGMicrobiology Research2036-74812025-05-0116510010.3390/microbiolres16050100Azo Dyes and the Microbial World: Synthesis, Breakdown, and BioactivityValery M. Dembitsky0Alexander O. Terent’ev1N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Leninsky Prospect, 47, 119334 Moscow, RussiaN.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Leninsky Prospect, 47, 119334 Moscow, RussiaThis review discusses natural and synthetic azo compounds found in bacteria, fungal endophytes, fungi, plants, and invertebrates. More than 100 of these compounds have demonstrated significant pharmacological activity, including antitumor, antimicrobial, and antibacterial effects. Using mathematical algorithms and the PASS program, researchers predict new potential applications based on their structure–activity relationships. This review emphasizes the importance of natural azo compounds as promising drug prototypes and key players in drug discovery. It also explores the synthesis and degradation of azo dyes and their potential uses in medicine, food, cosmetics, and related fields. Additionally, the role of microorganisms in producing natural azo compounds and their synthetic counterparts is examined, showcasing their potential in drug development and human health advancements.https://www.mdpi.com/2036-7481/16/5/100microorganismsbacteriaazo dyesazo compoundsactivitybreakdown |
| spellingShingle | Valery M. Dembitsky Alexander O. Terent’ev Azo Dyes and the Microbial World: Synthesis, Breakdown, and Bioactivity Microbiology Research microorganisms bacteria azo dyes azo compounds activity breakdown |
| title | Azo Dyes and the Microbial World: Synthesis, Breakdown, and Bioactivity |
| title_full | Azo Dyes and the Microbial World: Synthesis, Breakdown, and Bioactivity |
| title_fullStr | Azo Dyes and the Microbial World: Synthesis, Breakdown, and Bioactivity |
| title_full_unstemmed | Azo Dyes and the Microbial World: Synthesis, Breakdown, and Bioactivity |
| title_short | Azo Dyes and the Microbial World: Synthesis, Breakdown, and Bioactivity |
| title_sort | azo dyes and the microbial world synthesis breakdown and bioactivity |
| topic | microorganisms bacteria azo dyes azo compounds activity breakdown |
| url | https://www.mdpi.com/2036-7481/16/5/100 |
| work_keys_str_mv | AT valerymdembitsky azodyesandthemicrobialworldsynthesisbreakdownandbioactivity AT alexanderoterentev azodyesandthemicrobialworldsynthesisbreakdownandbioactivity |