MergeReference: A Tool for Merging Reference Panels for HLA Imputation
Recently developed computational methods allow the imputation of human leukocyte antigen (HLA) genes using intergenic single nucleotide polymorphism markers. To improve the imputation accuracy in HLA imputation, it is essential to increase the sample size and the diversity of alleles in the referenc...
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Main Authors: | Seungho Cook, Buhm Han |
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Format: | Article |
Language: | English |
Published: |
BioMed Central
2017-09-01
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Series: | Genomics & Informatics |
Subjects: | |
Online Access: | http://genominfo.org/upload/pdf/GI-2017-15-3-108.pdf |
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