THE STRATEGY OF ANTIMICROBIAL THERAPY OF ACUTE UNCOMPLICATED PYELONEPHRITIS FROM THE POSITION OF ETIOLOGICAL DATA
Abstract:Acute pyelonephritis is one of the common diseases both in outpatient and in the hospital practice. The leading causative agent of this disease is E. coli. Obstructive uropathy, foreign body, vesicoureteral reflux, sexual activity, use of local contraceptives contribute to the upward develo...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
QUASAR, LLC
2015-10-01
|
| Series: | Исследования и практика в медицине |
| Subjects: | |
| Online Access: | https://www.rpmj.ru/rpmj/article/view/84 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832568662146416640 |
|---|---|
| author | A. D. Kaprin A. A. Kostin S. V. Popov |
| author_facet | A. D. Kaprin A. A. Kostin S. V. Popov |
| author_sort | A. D. Kaprin |
| collection | DOAJ |
| description | Abstract:Acute pyelonephritis is one of the common diseases both in outpatient and in the hospital practice. The leading causative agent of this disease is E. coli. Obstructive uropathy, foreign body, vesicoureteral reflux, sexual activity, use of local contraceptives contribute to the upward development of urinary infection. The goals of antimicrobial therapy for acute uncomplicated pyelonephritis are: relief of symptoms, restoration of social activity, prevention of complications and relapse prevention. The choice of an antimicrobial agent in most cases is carried out empirically based on the data on the dominant pathogens and their regional resistance. In acute uncomplicated pyelonephritis duration of antimicrobial therapy should be 7–14 days. The drugs of choice for treatment of acute uncomplicated pyelonephritis non-severe in adults are ciprofloxacin and levofloxacin, ceftibuten and cefixime. Patients with acute uncomplicated pyelonephritis severe emergency hospitalization is shown in urological outpatient and parenteral antimicrobial therapy (carbapenems or protected aminopenicillins combined with or without amikacin) with subsequent conversion to oral drugs and infusion therapy. |
| format | Article |
| id | doaj-art-b846c6f1129a4c539b7788e32d83b26f |
| institution | Kabale University |
| issn | 2410-1893 |
| language | Russian |
| publishDate | 2015-10-01 |
| publisher | QUASAR, LLC |
| record_format | Article |
| series | Исследования и практика в медицине |
| spelling | doaj-art-b846c6f1129a4c539b7788e32d83b26f2025-02-03T00:57:41ZrusQUASAR, LLCИсследования и практика в медицине2410-18932015-10-0123596310.17709/2409-2231-2015-2-3-59-6357THE STRATEGY OF ANTIMICROBIAL THERAPY OF ACUTE UNCOMPLICATED PYELONEPHRITIS FROM THE POSITION OF ETIOLOGICAL DATAA. D. Kaprin0A. A. Kostin1S. V. Popov2NMRRC (Obninsk, Russian Federation)NMRRC (Obninsk, Russian Federation)NMRRC (Obninsk, Russian Federation)Abstract:Acute pyelonephritis is one of the common diseases both in outpatient and in the hospital practice. The leading causative agent of this disease is E. coli. Obstructive uropathy, foreign body, vesicoureteral reflux, sexual activity, use of local contraceptives contribute to the upward development of urinary infection. The goals of antimicrobial therapy for acute uncomplicated pyelonephritis are: relief of symptoms, restoration of social activity, prevention of complications and relapse prevention. The choice of an antimicrobial agent in most cases is carried out empirically based on the data on the dominant pathogens and their regional resistance. In acute uncomplicated pyelonephritis duration of antimicrobial therapy should be 7–14 days. The drugs of choice for treatment of acute uncomplicated pyelonephritis non-severe in adults are ciprofloxacin and levofloxacin, ceftibuten and cefixime. Patients with acute uncomplicated pyelonephritis severe emergency hospitalization is shown in urological outpatient and parenteral antimicrobial therapy (carbapenems or protected aminopenicillins combined with or without amikacin) with subsequent conversion to oral drugs and infusion therapy.https://www.rpmj.ru/rpmj/article/view/84pyelonephritisescherichia coliurinary tract infectionantimicrobial therapyfluoroquinolonescephalosporinscarbapenems |
| spellingShingle | A. D. Kaprin A. A. Kostin S. V. Popov THE STRATEGY OF ANTIMICROBIAL THERAPY OF ACUTE UNCOMPLICATED PYELONEPHRITIS FROM THE POSITION OF ETIOLOGICAL DATA Исследования и практика в медицине pyelonephritis escherichia coli urinary tract infection antimicrobial therapy fluoroquinolones cephalosporins carbapenems |
| title | THE STRATEGY OF ANTIMICROBIAL THERAPY OF ACUTE UNCOMPLICATED PYELONEPHRITIS FROM THE POSITION OF ETIOLOGICAL DATA |
| title_full | THE STRATEGY OF ANTIMICROBIAL THERAPY OF ACUTE UNCOMPLICATED PYELONEPHRITIS FROM THE POSITION OF ETIOLOGICAL DATA |
| title_fullStr | THE STRATEGY OF ANTIMICROBIAL THERAPY OF ACUTE UNCOMPLICATED PYELONEPHRITIS FROM THE POSITION OF ETIOLOGICAL DATA |
| title_full_unstemmed | THE STRATEGY OF ANTIMICROBIAL THERAPY OF ACUTE UNCOMPLICATED PYELONEPHRITIS FROM THE POSITION OF ETIOLOGICAL DATA |
| title_short | THE STRATEGY OF ANTIMICROBIAL THERAPY OF ACUTE UNCOMPLICATED PYELONEPHRITIS FROM THE POSITION OF ETIOLOGICAL DATA |
| title_sort | strategy of antimicrobial therapy of acute uncomplicated pyelonephritis from the position of etiological data |
| topic | pyelonephritis escherichia coli urinary tract infection antimicrobial therapy fluoroquinolones cephalosporins carbapenems |
| url | https://www.rpmj.ru/rpmj/article/view/84 |
| work_keys_str_mv | AT adkaprin thestrategyofantimicrobialtherapyofacuteuncomplicatedpyelonephritisfromthepositionofetiologicaldata AT aakostin thestrategyofantimicrobialtherapyofacuteuncomplicatedpyelonephritisfromthepositionofetiologicaldata AT svpopov thestrategyofantimicrobialtherapyofacuteuncomplicatedpyelonephritisfromthepositionofetiologicaldata AT adkaprin strategyofantimicrobialtherapyofacuteuncomplicatedpyelonephritisfromthepositionofetiologicaldata AT aakostin strategyofantimicrobialtherapyofacuteuncomplicatedpyelonephritisfromthepositionofetiologicaldata AT svpopov strategyofantimicrobialtherapyofacuteuncomplicatedpyelonephritisfromthepositionofetiologicaldata |