Insulin resistance compromises midbrain organoid neuronal activity and metabolic efficiency predisposing to Parkinson’s disease pathology
Growing evidence indicates that type 2 diabetes (T2D) is associated with an increased risk of developing Parkinson’s disease (PD) through shared disease mechanisms. Studies show that insulin resistance, which is the driving pathophysiological mechanism of T2D plays a major role in neurodegeneration...
Saved in:
Main Authors: | Alise Zagare, Janis Kurlovics, Catarina Almeida, Daniele Ferrante, Daniela Frangenberg, Armelle Vitali, Gemma Gomez-Giro, Christian Jäger, Paul Antony, Rashi Halder, Rejko Krüger, Enrico Glaab, Egils Stalidzans, Giuseppe Arena, Jens C Schwamborn |
---|---|
Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2025-01-01
|
Series: | Journal of Tissue Engineering |
Online Access: | https://doi.org/10.1177/20417314241295928 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Pathological Laughter as a Symptom of Midbrain Infarction
by: Ron Dabby, et al.
Published: (2004-01-01) -
Expression of catecholaminergic genes in the midbrain and prepulse inhibition in rats with a genetic catatonia
by: M. A. Ryazanova, et al.
Published: (2017-12-01) -
The Transnistrian Compromise?
by: I. S. PUTINTSEV
Published: (2010-02-01) -
Acute Myocardial Infarction and Predisposing Risk Factors
by: Julio Armando Sánchez Delgado, et al.
Published: (2023-11-01) -
Comparative Analysis of Spontaneous and Stimulus-Evoked Calcium Transients in Proliferating and Differentiating Human Midbrain-Derived Stem Cells
by: Torben Johansen, et al.
Published: (2017-01-01)