Stability of Ternary Drug–Drug–Drug Coamorphous Systems Obtained Through Mechanochemistry

Stability of Ternary Drug–Drug–Drug Coamorphous Systems Obtained Through Mechanochemistry

<b>Background/Objectives:</b> This study investigates the preparation of coamorphous systems composed entirely of active pharmaceutical ingredients (APIs), namely praziquantel, niclosamide, and mebendazole. The objective was to formulate and characterize binary and ternary coamorphous sy...

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Bibliographic Details
Main Authors: Ilenia D’Abbrunzo, Elisabetta Venier, Francesca Selmin, Irena Škorić, Enrico Bernardo, Giuseppe Procida, Beatrice Perissutti
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Pharmaceutics
Subjects:
ternary coamorphous
binary coamorphous
drug-to-drug-to-drug coamorphous
glass transition
physical stability
storage temperature
Online Access:https://www.mdpi.com/1999-4923/17/1/92
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