Single-cell RNA sequencing reveals heterogeneity of mucosa-associated invariant T cells in donor grafts and its diagnostic relevance in gastrointestinal graft-<i>versus</i>-host disease

Single-cell RNA sequencing reveals heterogeneity of mucosa-associated invariant T cells in donor grafts and its diagnostic relevance in gastrointestinal graft-<i>versus</i>-host disease

Granulocyte colony-stimulating factor (G-CSF) enhances acute graft-versus-host disease (aGVHD) prophylaxis in allogeneic hematopoietic stem cell transplantation (allo-HSCT) by inducing T cell tolerance and altering graft cell composition. Previous studies have shown that the number of mucosa-associ...

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Bibliographic Details
Main Authors: Mengge Gao, Kainan Zhang, Siqi Li, Huidong Guo, Yuqian Sun, Jun Kong, Tingting Han, Yingjun Chang, Xiaojun Huang, Xiaosu Zhao
Format: Article
Language:English
Published: Ferrata Storti Foundation 2025-07-01
Series:Haematologica
Online Access:https://haematologica.org/article/view/12193
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https://haematologica.org/article/view/12193

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