Redo Aortic Valve Replacement After Prior Transcatheter versus Surgical Aortic Valve Replacement: Insights from Western Experience

Introduction: The demand for reoperation on the aortic valve in Albania is rising, mirroring the increasing average age of the population and the subsequent rise in patients requiring aortic valve surgery. This trend underscores the need for this informative article, which aims to provide insights i...

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Main Authors: Arber Aliu, Klodiana Durici, Ira Lazo, Altin Veshti
Format: Article
Language:English
Published: Albanian Society for Trauma and Emergency Surgery 2025-01-01
Series:Albanian Journal of Trauma and Emergency Surgery
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Online Access:http://journal.astes.org.al/AJTES/index.php/AJTES/article/view/440
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author Arber Aliu
Klodiana Durici
Ira Lazo
Altin Veshti
author_facet Arber Aliu
Klodiana Durici
Ira Lazo
Altin Veshti
author_sort Arber Aliu
collection DOAJ
description Introduction: The demand for reoperation on the aortic valve in Albania is rising, mirroring the increasing average age of the population and the subsequent rise in patients requiring aortic valve surgery. This trend underscores the need for this informative article, which aims to provide insights into the risks and outcomes of aortic valve reoperations, particularly in light of efforts by interventional cardiologists to expand the indications for TAVR to younger and lower-risk patients. Data from the Society of Thoracic Surgeons (STS) National Database reveal results that warrant attention, with concerns over reoperations after TAVR growing, mainly due to the uncertain feasibility of repeat TAVR.  This article presents a novel perspective on the risks associated with surgical aortic valve replacement (SAVR) after prior TAVR or SAVR. It underscores the urgent need to develop an optimal strategy for managing these patients and offers fresh insight.  Material and Methods: Our research, based on a comprehensive analysis of data from the Society of Thoracic Surgeons in the USA's 10-year database, included individuals who underwent bioprosthetic SAVR following prior TAVR and/or SAVR. Our analyses, which included total and isolated SAVR groups, focused on the primary outcome of operative mortality, ensuring the reliability and thoroughness of our study.  Results: The study included 31,106 patients who underwent SAVR. Among them, 1,126 had prior TAVR (TAVR-SAVR), 674 had undergone SAVR followed by TAVR and SAVR (SAVR-TAVR-SAVR), and 29,306 had undergone prior SAVR (SAVR-SAVR). Matched analysis for isolated SAVR cases showed a 1.74-fold higher operative mortality for TAVR-SAVR than SAVR-SAVR (P = 0.020). In our center, 5 cases have been performed in the last two years with excellent results, no losses, and operating times close to the first-time interventions. Conclusions: This study's findings significantly contribute to the field. They could influence clinical practice, particularly for patients with longer life expectancies and anatomy unsuitable for TAVR. They suggest an initial SAVR approach may provide better results even in necessary surgical re-interventions on the aortic valve.
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language English
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spelling doaj-art-b827b48d77554ec392f5e98922d517cf2025-01-19T14:24:38ZengAlbanian Society for Trauma and Emergency SurgeryAlbanian Journal of Trauma and Emergency Surgery2521-87782616-49222025-01-019110.32391/ajtes.v9i1.440Redo Aortic Valve Replacement After Prior Transcatheter versus Surgical Aortic Valve Replacement: Insights from Western ExperienceArber Aliu0Klodiana Durici1Ira Lazo2Altin Veshti3Department of Cardiac Surgery, Mother Teresa University Hospital Center, Tirana, ALBANIAService of Cardiac Surgery, University Hospital Center” Mother Theresa”, Tirana, AlbaniaService of Cardiac Surgery, University Hospital Center” Mother Theresa”, Tirana, AlbaniaService of Cardiac Surgery, University Hospital Center” Mother Theresa”, Tirana, AlbaniaIntroduction: The demand for reoperation on the aortic valve in Albania is rising, mirroring the increasing average age of the population and the subsequent rise in patients requiring aortic valve surgery. This trend underscores the need for this informative article, which aims to provide insights into the risks and outcomes of aortic valve reoperations, particularly in light of efforts by interventional cardiologists to expand the indications for TAVR to younger and lower-risk patients. Data from the Society of Thoracic Surgeons (STS) National Database reveal results that warrant attention, with concerns over reoperations after TAVR growing, mainly due to the uncertain feasibility of repeat TAVR.  This article presents a novel perspective on the risks associated with surgical aortic valve replacement (SAVR) after prior TAVR or SAVR. It underscores the urgent need to develop an optimal strategy for managing these patients and offers fresh insight.  Material and Methods: Our research, based on a comprehensive analysis of data from the Society of Thoracic Surgeons in the USA's 10-year database, included individuals who underwent bioprosthetic SAVR following prior TAVR and/or SAVR. Our analyses, which included total and isolated SAVR groups, focused on the primary outcome of operative mortality, ensuring the reliability and thoroughness of our study.  Results: The study included 31,106 patients who underwent SAVR. Among them, 1,126 had prior TAVR (TAVR-SAVR), 674 had undergone SAVR followed by TAVR and SAVR (SAVR-TAVR-SAVR), and 29,306 had undergone prior SAVR (SAVR-SAVR). Matched analysis for isolated SAVR cases showed a 1.74-fold higher operative mortality for TAVR-SAVR than SAVR-SAVR (P = 0.020). In our center, 5 cases have been performed in the last two years with excellent results, no losses, and operating times close to the first-time interventions. Conclusions: This study's findings significantly contribute to the field. They could influence clinical practice, particularly for patients with longer life expectancies and anatomy unsuitable for TAVR. They suggest an initial SAVR approach may provide better results even in necessary surgical re-interventions on the aortic valve. http://journal.astes.org.al/AJTES/index.php/AJTES/article/view/440TAVRSAVRAortic Valve Reoperation
spellingShingle Arber Aliu
Klodiana Durici
Ira Lazo
Altin Veshti
Redo Aortic Valve Replacement After Prior Transcatheter versus Surgical Aortic Valve Replacement: Insights from Western Experience
Albanian Journal of Trauma and Emergency Surgery
TAVR
SAVR
Aortic Valve Reoperation
title Redo Aortic Valve Replacement After Prior Transcatheter versus Surgical Aortic Valve Replacement: Insights from Western Experience
title_full Redo Aortic Valve Replacement After Prior Transcatheter versus Surgical Aortic Valve Replacement: Insights from Western Experience
title_fullStr Redo Aortic Valve Replacement After Prior Transcatheter versus Surgical Aortic Valve Replacement: Insights from Western Experience
title_full_unstemmed Redo Aortic Valve Replacement After Prior Transcatheter versus Surgical Aortic Valve Replacement: Insights from Western Experience
title_short Redo Aortic Valve Replacement After Prior Transcatheter versus Surgical Aortic Valve Replacement: Insights from Western Experience
title_sort redo aortic valve replacement after prior transcatheter versus surgical aortic valve replacement insights from western experience
topic TAVR
SAVR
Aortic Valve Reoperation
url http://journal.astes.org.al/AJTES/index.php/AJTES/article/view/440
work_keys_str_mv AT arberaliu redoaorticvalvereplacementafterpriortranscatheterversussurgicalaorticvalvereplacementinsightsfromwesternexperience
AT klodianadurici redoaorticvalvereplacementafterpriortranscatheterversussurgicalaorticvalvereplacementinsightsfromwesternexperience
AT iralazo redoaorticvalvereplacementafterpriortranscatheterversussurgicalaorticvalvereplacementinsightsfromwesternexperience
AT altinveshti redoaorticvalvereplacementafterpriortranscatheterversussurgicalaorticvalvereplacementinsightsfromwesternexperience