Unruptured Cerebral Aneurysms: Evaluation and Management
The evolution of imaging techniques and their increased use in clinical practice have led to a higher detection rate of unruptured intracranial aneurysms. The diagnosis of an unruptured intracranial aneurysm is a source of significant stress to the patient because of the concerns for aneurysmal rupt...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1155/2015/954954 |
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| _version_ | 1832552094387666944 |
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| author | Norman Ajiboye Nohra Chalouhi Robert M. Starke Mario Zanaty Rodney Bell |
| author_facet | Norman Ajiboye Nohra Chalouhi Robert M. Starke Mario Zanaty Rodney Bell |
| author_sort | Norman Ajiboye |
| collection | DOAJ |
| description | The evolution of imaging techniques and their increased use in clinical practice have led to a higher detection rate of unruptured intracranial aneurysms. The diagnosis of an unruptured intracranial aneurysm is a source of significant stress to the patient because of the concerns for aneurysmal rupture, which is associated with substantial rates of morbidity and mortality. Therefore, it is important that decisions regarding optimum management are made based on the comparison of the risk of aneurysmal rupture with the risk associated with intervention. This review provides a comprehensive overview of the epidemiology, pathophysiology, natural history, clinical presentation, diagnosis, and management options for unruptured intracranial aneurysms based on the current evidence in the literature. Furthermore, the authors discuss the genetic abnormalities associated with intracranial aneurysm and current guidelines for screening in patients with a family history of intracranial aneurysms. Since there is significant controversy in the optimum management of small unruptured intracranial aneurysms, we provided a systematic approach to their management based on patient and aneurysm characteristics as well as the risks and benefits of intervention. |
| format | Article |
| id | doaj-art-b8220524478b40549a4ff2b8265cf726 |
| institution | Kabale University |
| issn | 2356-6140 1537-744X |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-b8220524478b40549a4ff2b8265cf7262025-02-03T05:59:34ZengWileyThe Scientific World Journal2356-61401537-744X2015-01-01201510.1155/2015/954954954954Unruptured Cerebral Aneurysms: Evaluation and ManagementNorman Ajiboye0Nohra Chalouhi1Robert M. Starke2Mario Zanaty3Rodney Bell4Department of Neurological Surgery, Division of Neurovascular Surgery and Endovascular Neurosurgery, Thomas Jefferson University Hospital, Philadelphia, PA 19107, USADepartment of Neurological Surgery, Division of Neurovascular Surgery and Endovascular Neurosurgery, Thomas Jefferson University Hospital, Philadelphia, PA 19107, USADepartment of Neurosurgery, University of Virginia, Charlottesville, VA 22903, USADepartment of Neurological Surgery, Division of Neurovascular Surgery and Endovascular Neurosurgery, Thomas Jefferson University Hospital, Philadelphia, PA 19107, USADepartment of Neurological Surgery, Division of Neurovascular Surgery and Endovascular Neurosurgery, Thomas Jefferson University Hospital, Philadelphia, PA 19107, USAThe evolution of imaging techniques and their increased use in clinical practice have led to a higher detection rate of unruptured intracranial aneurysms. The diagnosis of an unruptured intracranial aneurysm is a source of significant stress to the patient because of the concerns for aneurysmal rupture, which is associated with substantial rates of morbidity and mortality. Therefore, it is important that decisions regarding optimum management are made based on the comparison of the risk of aneurysmal rupture with the risk associated with intervention. This review provides a comprehensive overview of the epidemiology, pathophysiology, natural history, clinical presentation, diagnosis, and management options for unruptured intracranial aneurysms based on the current evidence in the literature. Furthermore, the authors discuss the genetic abnormalities associated with intracranial aneurysm and current guidelines for screening in patients with a family history of intracranial aneurysms. Since there is significant controversy in the optimum management of small unruptured intracranial aneurysms, we provided a systematic approach to their management based on patient and aneurysm characteristics as well as the risks and benefits of intervention.http://dx.doi.org/10.1155/2015/954954 |
| spellingShingle | Norman Ajiboye Nohra Chalouhi Robert M. Starke Mario Zanaty Rodney Bell Unruptured Cerebral Aneurysms: Evaluation and Management The Scientific World Journal |
| title | Unruptured Cerebral Aneurysms: Evaluation and Management |
| title_full | Unruptured Cerebral Aneurysms: Evaluation and Management |
| title_fullStr | Unruptured Cerebral Aneurysms: Evaluation and Management |
| title_full_unstemmed | Unruptured Cerebral Aneurysms: Evaluation and Management |
| title_short | Unruptured Cerebral Aneurysms: Evaluation and Management |
| title_sort | unruptured cerebral aneurysms evaluation and management |
| url | http://dx.doi.org/10.1155/2015/954954 |
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