Analytic and clinical validity of thyroid nodule mutational profiling using droplet digital polymerase chain reaction
Abstract Background Recent guidelines for the management of thyroid nodules incorporate mutation testing as an adjunct for surgical decision-making, however current tests are costly with limited accuracy. Droplet digital PCR (ddPCR) is an ultrasensitive method of nucleic acid detection that is parti...
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Main Authors: | Vincent L. Biron, Ashlee Matkin, Morris Kostiuk, Jordana Williams, David W. Cote, Jeffrey Harris, Hadi Seikaly, Daniel A. O’Connell |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2018-09-01
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Series: | Journal of Otolaryngology - Head and Neck Surgery |
Online Access: | http://link.springer.com/article/10.1186/s40463-018-0299-2 |
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