Predictors of a metabolically unhealthy obesity

Over the past 50 years, the number of obese people has increased many times. Despite the excess weight, many patients may be metabolically healthy. But studies show that this condition is an intermediate stage ending with a metabolically unhealthy phenotype, which is associated with an increase in t...

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Bibliographic Details
Main Authors: Yu. V. Burenkov, V. I. Shevtsova, O. N. Krasnorutskaya, Yu. A. Kotova
Format: Article
Language:Russian
Published: «SILICEA-POLIGRAF» LLC 2025-03-01
Series:Кардиоваскулярная терапия и профилактика
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Online Access:https://cardiovascular.elpub.ru/jour/article/view/4212
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Summary:Over the past 50 years, the number of obese people has increased many times. Despite the excess weight, many patients may be metabolically healthy. But studies show that this condition is an intermediate stage ending with a metabolically unhealthy phenotype, which is associated with an increase in the incidence of cardiovascular events. The concept of metabolically unhealthy obesity is characterized by altered levels of various biomarkers, the significance of which in the context of predicting a metabolically unhealthy phenotype remains to be studied. The review is devoted to the analysis of modern research data on the role of hyperuricemia, gut microbiota and its metabolites, adipocytokines, as well as an assessment of their relationship with a metabolically unhealthy obesity.
ISSN:1728-8800
2619-0125