The Infant Skin Barrier: Can We Preserve, Protect, and Enhance the Barrier?
Infant skin is different from adult in structure, function, and composition. Despite these differences, the skin barrier is competent at birth in healthy, full-term neonates. The primary focus of this paper is on the developing skin barrier in healthy, full-term neonates and infants. Additionally, a...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Dermatology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2012/198789 |
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| author | Lorena S. Telofski A. Peter Morello M. Catherine Mack Correa Georgios N. Stamatas |
| author_facet | Lorena S. Telofski A. Peter Morello M. Catherine Mack Correa Georgios N. Stamatas |
| author_sort | Lorena S. Telofski |
| collection | DOAJ |
| description | Infant skin is different from adult in structure, function, and composition. Despite these differences, the skin barrier is competent at birth in healthy, full-term neonates. The primary focus of this paper is on the developing skin barrier in healthy, full-term neonates and infants. Additionally, a brief discussion of the properties of the skin barrier in premature neonates and infants with abnormal skin conditions (i.e., atopic dermatitis and eczema) is included. As infant skin continues to mature through the first years of life, it is important that skin care products (e.g., cleansers and emollients) are formulated appropriately. Ideally, products that are used on infants should not interfere with skin surface pH or perturb the skin barrier. For cleansers, this can be achieved by choosing the right type of surfactant, by blending surfactants, or by blending hydrophobically-modified polymers (HMPs) with surfactants to increase product mildness. Similarly, choosing the right type of oil for emollients is important. Unlike some vegetable oils, mineral oil is more stable and is not subject to oxidation and hydrolysis. Although emollients can improve the skin barrier, more studies are needed to determine the potential long-term benefits of using emollients on healthy, full-term neonates and infants. |
| format | Article |
| id | doaj-art-b8036489d4334ccc857d3f7b69e7a385 |
| institution | Kabale University |
| issn | 1687-6105 1687-6113 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Dermatology Research and Practice |
| spelling | doaj-art-b8036489d4334ccc857d3f7b69e7a3852025-02-03T01:32:48ZengWileyDermatology Research and Practice1687-61051687-61132012-01-01201210.1155/2012/198789198789The Infant Skin Barrier: Can We Preserve, Protect, and Enhance the Barrier?Lorena S. Telofski0A. Peter Morello1M. Catherine Mack Correa2Georgios N. Stamatas3JOHNSON & JOHNSON Consumer Companies, Inc., 199 Grandview Road, Skillman, NJ 08558, USAEvidence Scientific Solutions, 123 South Broad Street, Suite 1670, Philadelphia, PA 19109, USAJOHNSON & JOHNSON Consumer Companies, Inc., 199 Grandview Road, Skillman, NJ 08558, USAJOHNSON & JOHNSON Santé Beauté France, 1 rue Camille Desmoulins, 92787 Issy-les-Moulineaux, FranceInfant skin is different from adult in structure, function, and composition. Despite these differences, the skin barrier is competent at birth in healthy, full-term neonates. The primary focus of this paper is on the developing skin barrier in healthy, full-term neonates and infants. Additionally, a brief discussion of the properties of the skin barrier in premature neonates and infants with abnormal skin conditions (i.e., atopic dermatitis and eczema) is included. As infant skin continues to mature through the first years of life, it is important that skin care products (e.g., cleansers and emollients) are formulated appropriately. Ideally, products that are used on infants should not interfere with skin surface pH or perturb the skin barrier. For cleansers, this can be achieved by choosing the right type of surfactant, by blending surfactants, or by blending hydrophobically-modified polymers (HMPs) with surfactants to increase product mildness. Similarly, choosing the right type of oil for emollients is important. Unlike some vegetable oils, mineral oil is more stable and is not subject to oxidation and hydrolysis. Although emollients can improve the skin barrier, more studies are needed to determine the potential long-term benefits of using emollients on healthy, full-term neonates and infants.http://dx.doi.org/10.1155/2012/198789 |
| spellingShingle | Lorena S. Telofski A. Peter Morello M. Catherine Mack Correa Georgios N. Stamatas The Infant Skin Barrier: Can We Preserve, Protect, and Enhance the Barrier? Dermatology Research and Practice |
| title | The Infant Skin Barrier: Can We Preserve, Protect, and Enhance the Barrier? |
| title_full | The Infant Skin Barrier: Can We Preserve, Protect, and Enhance the Barrier? |
| title_fullStr | The Infant Skin Barrier: Can We Preserve, Protect, and Enhance the Barrier? |
| title_full_unstemmed | The Infant Skin Barrier: Can We Preserve, Protect, and Enhance the Barrier? |
| title_short | The Infant Skin Barrier: Can We Preserve, Protect, and Enhance the Barrier? |
| title_sort | infant skin barrier can we preserve protect and enhance the barrier |
| url | http://dx.doi.org/10.1155/2012/198789 |
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