Genome Assembly and Genome Annotation of Leishmania martiniquensis Isolated from a Leishmaniasis Patient in Thailand
Leishmaniasis is a parasitic disease caused by Leishmania spp. with worldwide distribution. Autochthonous leishmaniasis has been reported to result from the infection by Leishmania martiniquensis in Thailand. This species was isolated in culture and subjected to high-throughput whole-genome sequenci...
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| Format: | Article |
| Language: | English |
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Wiley
2022-01-01
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| Series: | Journal of Parasitology Research |
| Online Access: | http://dx.doi.org/10.1155/2022/8768574 |
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| author | Songtham Anuntakarun Atchara Phumee Vorthon Sawaswong Kesmanee Praianantathavorn Witthaya Poomipak Rungrat Jitvaropas Padet Siriyasatien Sunchai Payungporn |
| author_facet | Songtham Anuntakarun Atchara Phumee Vorthon Sawaswong Kesmanee Praianantathavorn Witthaya Poomipak Rungrat Jitvaropas Padet Siriyasatien Sunchai Payungporn |
| author_sort | Songtham Anuntakarun |
| collection | DOAJ |
| description | Leishmaniasis is a parasitic disease caused by Leishmania spp. with worldwide distribution. Autochthonous leishmaniasis has been reported to result from the infection by Leishmania martiniquensis in Thailand. This species was isolated in culture and subjected to high-throughput whole-genome sequencing. A total of 30.8 Mb in 36 chromosomes of the whole genome was assembled, annotated, and characterized. The L. martiniquensis under study was shown to segregate into the same clade and thus closely related to the previously identified L. martiniquensis (LU_Lmar_1.0), as determined by phylogenetic analysis of their genomic sequences along with those of representative kinetoplastid species. The total number of open reading frames genomewide predicts 8,209 protein-coding genes, of which 359 are putative virulence factors, including two previously known, e.g., cysteine proteinase C and superoxide dismutase B1. The results obtained from this study will be useful for further annotation and comparison with other Leishmania martiniquensis in the future. |
| format | Article |
| id | doaj-art-b7f3feb7479d4587be55f9f774c245d9 |
| institution | Kabale University |
| issn | 2090-0031 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Parasitology Research |
| spelling | doaj-art-b7f3feb7479d4587be55f9f774c245d92025-02-03T01:09:52ZengWileyJournal of Parasitology Research2090-00312022-01-01202210.1155/2022/8768574Genome Assembly and Genome Annotation of Leishmania martiniquensis Isolated from a Leishmaniasis Patient in ThailandSongtham Anuntakarun0Atchara Phumee1Vorthon Sawaswong2Kesmanee Praianantathavorn3Witthaya Poomipak4Rungrat Jitvaropas5Padet Siriyasatien6Sunchai Payungporn7Program in Bioinformatics and Computational BiologyDepartment of Medical TechnologyProgram in Bioinformatics and Computational BiologyDepartment of BiochemistryResearch AffairsDivision of BiochemistryVector Biology and Vector Borne Disease Research UnitDepartment of BiochemistryLeishmaniasis is a parasitic disease caused by Leishmania spp. with worldwide distribution. Autochthonous leishmaniasis has been reported to result from the infection by Leishmania martiniquensis in Thailand. This species was isolated in culture and subjected to high-throughput whole-genome sequencing. A total of 30.8 Mb in 36 chromosomes of the whole genome was assembled, annotated, and characterized. The L. martiniquensis under study was shown to segregate into the same clade and thus closely related to the previously identified L. martiniquensis (LU_Lmar_1.0), as determined by phylogenetic analysis of their genomic sequences along with those of representative kinetoplastid species. The total number of open reading frames genomewide predicts 8,209 protein-coding genes, of which 359 are putative virulence factors, including two previously known, e.g., cysteine proteinase C and superoxide dismutase B1. The results obtained from this study will be useful for further annotation and comparison with other Leishmania martiniquensis in the future.http://dx.doi.org/10.1155/2022/8768574 |
| spellingShingle | Songtham Anuntakarun Atchara Phumee Vorthon Sawaswong Kesmanee Praianantathavorn Witthaya Poomipak Rungrat Jitvaropas Padet Siriyasatien Sunchai Payungporn Genome Assembly and Genome Annotation of Leishmania martiniquensis Isolated from a Leishmaniasis Patient in Thailand Journal of Parasitology Research |
| title | Genome Assembly and Genome Annotation of Leishmania martiniquensis Isolated from a Leishmaniasis Patient in Thailand |
| title_full | Genome Assembly and Genome Annotation of Leishmania martiniquensis Isolated from a Leishmaniasis Patient in Thailand |
| title_fullStr | Genome Assembly and Genome Annotation of Leishmania martiniquensis Isolated from a Leishmaniasis Patient in Thailand |
| title_full_unstemmed | Genome Assembly and Genome Annotation of Leishmania martiniquensis Isolated from a Leishmaniasis Patient in Thailand |
| title_short | Genome Assembly and Genome Annotation of Leishmania martiniquensis Isolated from a Leishmaniasis Patient in Thailand |
| title_sort | genome assembly and genome annotation of leishmania martiniquensis isolated from a leishmaniasis patient in thailand |
| url | http://dx.doi.org/10.1155/2022/8768574 |
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