Screening for Gastric and Small Intestinal Mucosal Injury with Magnetically Controlled Capsule Endoscopy in Asymptomatic Patients Taking Enteric-Coated Aspirin
Objective. To investigate gastric and small intestinal mucosal injury in asymptomatic patients taking enteric-coated aspirin using magnetically controlled capsule endoscopy. Methods. Patients taking enteric-coated aspirin (aspirin group) and healthy controls (control group) were recruited from Beiji...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Gastroenterology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2018/2524698 |
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| _version_ | 1832567958322282496 |
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| author | Xue Chen Feng Gao Jie Zhang |
| author_facet | Xue Chen Feng Gao Jie Zhang |
| author_sort | Xue Chen |
| collection | DOAJ |
| description | Objective. To investigate gastric and small intestinal mucosal injury in asymptomatic patients taking enteric-coated aspirin using magnetically controlled capsule endoscopy. Methods. Patients taking enteric-coated aspirin (aspirin group) and healthy controls (control group) were recruited from Beijing Anzhen Hospital, Capital Medical University, between September 2017 and May 2018, and undertook magnetically controlled capsule endoscopy. Results. Twenty-six subjects were recruited to the aspirin group and twenty-six to the control group; the median Gastrointestinal Symptom Rating Scale scores were 3.50 and 3.00 (P=0.200), the median gastric Lanza scores were 2.50 and 1.00 (P<0.001), the small intestinal Lanza scores were 1.00 and 0.00 (P<0.001), the gastric controlled examination times were 50.0 and 51.0 min (P=0.171), the small intestinal transit times were 240.0 and 238.0 min (P=0.654), and the capsule excretion times were 24.0 and 24.0 hours (P=0.956), respectively. Conclusions. Rates of gastric and small intestinal mucosal injuries were significantly higher in patients without obvious gastrointestinal symptoms taking enteric-coated aspirin compared to healthy controls. Magnetically controlled capsule endoscopy constitutes a safe, real-time screening modality for gastric and small intestinal mucosal injury in patients taking enteric-coated aspirin. |
| format | Article |
| id | doaj-art-b7d6ae9c64cb4d89871f5c56b97ae522 |
| institution | Kabale University |
| issn | 1687-6121 1687-630X |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Gastroenterology Research and Practice |
| spelling | doaj-art-b7d6ae9c64cb4d89871f5c56b97ae5222025-02-03T01:00:09ZengWileyGastroenterology Research and Practice1687-61211687-630X2018-01-01201810.1155/2018/25246982524698Screening for Gastric and Small Intestinal Mucosal Injury with Magnetically Controlled Capsule Endoscopy in Asymptomatic Patients Taking Enteric-Coated AspirinXue Chen0Feng Gao1Jie Zhang2Digestive Department, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, ChinaDigestive Department, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, ChinaDigestive Department, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, ChinaObjective. To investigate gastric and small intestinal mucosal injury in asymptomatic patients taking enteric-coated aspirin using magnetically controlled capsule endoscopy. Methods. Patients taking enteric-coated aspirin (aspirin group) and healthy controls (control group) were recruited from Beijing Anzhen Hospital, Capital Medical University, between September 2017 and May 2018, and undertook magnetically controlled capsule endoscopy. Results. Twenty-six subjects were recruited to the aspirin group and twenty-six to the control group; the median Gastrointestinal Symptom Rating Scale scores were 3.50 and 3.00 (P=0.200), the median gastric Lanza scores were 2.50 and 1.00 (P<0.001), the small intestinal Lanza scores were 1.00 and 0.00 (P<0.001), the gastric controlled examination times were 50.0 and 51.0 min (P=0.171), the small intestinal transit times were 240.0 and 238.0 min (P=0.654), and the capsule excretion times were 24.0 and 24.0 hours (P=0.956), respectively. Conclusions. Rates of gastric and small intestinal mucosal injuries were significantly higher in patients without obvious gastrointestinal symptoms taking enteric-coated aspirin compared to healthy controls. Magnetically controlled capsule endoscopy constitutes a safe, real-time screening modality for gastric and small intestinal mucosal injury in patients taking enteric-coated aspirin.http://dx.doi.org/10.1155/2018/2524698 |
| spellingShingle | Xue Chen Feng Gao Jie Zhang Screening for Gastric and Small Intestinal Mucosal Injury with Magnetically Controlled Capsule Endoscopy in Asymptomatic Patients Taking Enteric-Coated Aspirin Gastroenterology Research and Practice |
| title | Screening for Gastric and Small Intestinal Mucosal Injury with Magnetically Controlled Capsule Endoscopy in Asymptomatic Patients Taking Enteric-Coated Aspirin |
| title_full | Screening for Gastric and Small Intestinal Mucosal Injury with Magnetically Controlled Capsule Endoscopy in Asymptomatic Patients Taking Enteric-Coated Aspirin |
| title_fullStr | Screening for Gastric and Small Intestinal Mucosal Injury with Magnetically Controlled Capsule Endoscopy in Asymptomatic Patients Taking Enteric-Coated Aspirin |
| title_full_unstemmed | Screening for Gastric and Small Intestinal Mucosal Injury with Magnetically Controlled Capsule Endoscopy in Asymptomatic Patients Taking Enteric-Coated Aspirin |
| title_short | Screening for Gastric and Small Intestinal Mucosal Injury with Magnetically Controlled Capsule Endoscopy in Asymptomatic Patients Taking Enteric-Coated Aspirin |
| title_sort | screening for gastric and small intestinal mucosal injury with magnetically controlled capsule endoscopy in asymptomatic patients taking enteric coated aspirin |
| url | http://dx.doi.org/10.1155/2018/2524698 |
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