Evaluation of Retinal Layers and Choroidal Structures Using Optical Coherence Tomography in Alopecia Areata
Objective: To evaluate the macula, retinal nerve fiber layer (RNFL), retinal layers, and choroidal thickness (CT) using spectral domain optical coherence tomography (SD-OCT) in patients with alopecia areata (AA). Methods: The right eyes of 42 AA patients (17 women, 25 men) and 42 controls (18 women,...
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Galenos Publishing House
2023-06-01
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| Series: | Medeniyet Medical Journal |
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| Online Access: | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=medeniyet&un=MEDJ-58269 |
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| author | Burak OREN Gozde AKSOY AYDEMIR Serkan DUZAYAK Hasan KIZILTOPRAK |
| author_facet | Burak OREN Gozde AKSOY AYDEMIR Serkan DUZAYAK Hasan KIZILTOPRAK |
| author_sort | Burak OREN |
| collection | DOAJ |
| description | Objective: To evaluate the macula, retinal nerve fiber layer (RNFL), retinal layers, and choroidal thickness (CT) using spectral domain optical coherence tomography (SD-OCT) in patients with alopecia areata (AA).
Methods: The right eyes of 42 AA patients (17 women, 25 men) and 42 controls (18 women, 24 men) were included in the study. Each subject underwent thorough ophthalmic examination and SD-OCT (Heidelberg Engineering) measurements. Central macular thickness (CMT), RNFL, the average thicknesses of the ganglion cell layer (GCL), inner plexiform layer (IPL), inner nuclear layer (INL), outer plexiform layer (OPL), outer nuclear layer (ONL), retinal pigment epithelium (RPE), inner retinal layers (IRL), photoreceptor layers (PRL) as well as subfoveal, temporal and nasal CT were measured.
Results: In all sectors, no significant difference was observed between the AA group and the control group with regard to the mean values for CMT and RNFL (p>0.05, for all). There was not a significant difference between the AA group and the control group with regard to the thickness of the GCL, IPL, INL, OPL, ONL, RPE, IRL, and PRL (p>0.05 for all). CT at the subfoveal, temporal, and nasal regions was significantly thicker in the AA group than in the control group (p<0.05 for all).
Conclusions: Along with T-lymphocyte-mediated hair follicle damage, choroidal melanocyte damage and inflammation can also be observed in AA patients. CT may increase secondary to melanocyte inflammation in AA patients. |
| format | Article |
| id | doaj-art-b7d0d2652ca041e19e9bd2ee122e6d2f |
| institution | Kabale University |
| issn | 2149-2042 2149-4606 |
| language | English |
| publishDate | 2023-06-01 |
| publisher | Galenos Publishing House |
| record_format | Article |
| series | Medeniyet Medical Journal |
| spelling | doaj-art-b7d0d2652ca041e19e9bd2ee122e6d2f2025-01-30T07:04:38ZengGalenos Publishing HouseMedeniyet Medical Journal2149-20422149-46062023-06-0138214014710.4274/MMJ.galenos.2023.58269MEDJ-58269Evaluation of Retinal Layers and Choroidal Structures Using Optical Coherence Tomography in Alopecia AreataBurak OREN0Gozde AKSOY AYDEMIR1Serkan DUZAYAK2Hasan KIZILTOPRAK3Adıyaman University Faculty of Medicine, Department of Ophthalmology, Adıyaman, TurkeyAdıyaman University Faculty of Medicine, Department of Ophthalmology, Adıyaman, TurkeyKozan State Hospital, Clinic of Dermatology, Adana, TurkeyAdıyaman University Faculty of Medicine, Department of Ophthalmology, Adıyaman, TurkeyObjective: To evaluate the macula, retinal nerve fiber layer (RNFL), retinal layers, and choroidal thickness (CT) using spectral domain optical coherence tomography (SD-OCT) in patients with alopecia areata (AA). Methods: The right eyes of 42 AA patients (17 women, 25 men) and 42 controls (18 women, 24 men) were included in the study. Each subject underwent thorough ophthalmic examination and SD-OCT (Heidelberg Engineering) measurements. Central macular thickness (CMT), RNFL, the average thicknesses of the ganglion cell layer (GCL), inner plexiform layer (IPL), inner nuclear layer (INL), outer plexiform layer (OPL), outer nuclear layer (ONL), retinal pigment epithelium (RPE), inner retinal layers (IRL), photoreceptor layers (PRL) as well as subfoveal, temporal and nasal CT were measured. Results: In all sectors, no significant difference was observed between the AA group and the control group with regard to the mean values for CMT and RNFL (p>0.05, for all). There was not a significant difference between the AA group and the control group with regard to the thickness of the GCL, IPL, INL, OPL, ONL, RPE, IRL, and PRL (p>0.05 for all). CT at the subfoveal, temporal, and nasal regions was significantly thicker in the AA group than in the control group (p<0.05 for all). Conclusions: Along with T-lymphocyte-mediated hair follicle damage, choroidal melanocyte damage and inflammation can also be observed in AA patients. CT may increase secondary to melanocyte inflammation in AA patients.https://jag.journalagent.com/z4/download_fulltext.asp?pdir=medeniyet&un=MEDJ-58269alopecia areatachoroidal thicknessretinal nerve fiber layeroptical coherence tomography |
| spellingShingle | Burak OREN Gozde AKSOY AYDEMIR Serkan DUZAYAK Hasan KIZILTOPRAK Evaluation of Retinal Layers and Choroidal Structures Using Optical Coherence Tomography in Alopecia Areata Medeniyet Medical Journal alopecia areata choroidal thickness retinal nerve fiber layer optical coherence tomography |
| title | Evaluation of Retinal Layers and Choroidal Structures Using Optical Coherence Tomography in Alopecia Areata |
| title_full | Evaluation of Retinal Layers and Choroidal Structures Using Optical Coherence Tomography in Alopecia Areata |
| title_fullStr | Evaluation of Retinal Layers and Choroidal Structures Using Optical Coherence Tomography in Alopecia Areata |
| title_full_unstemmed | Evaluation of Retinal Layers and Choroidal Structures Using Optical Coherence Tomography in Alopecia Areata |
| title_short | Evaluation of Retinal Layers and Choroidal Structures Using Optical Coherence Tomography in Alopecia Areata |
| title_sort | evaluation of retinal layers and choroidal structures using optical coherence tomography in alopecia areata |
| topic | alopecia areata choroidal thickness retinal nerve fiber layer optical coherence tomography |
| url | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=medeniyet&un=MEDJ-58269 |
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