Identification of YAP regulators through high-throughput screening and NanoBiT-based validation-drug repositioning for cancer therapy
Yes-associated protein (YAP), a key co-transcription factor of the Hippo pathway, is a promising drug target for cancer therapy due to its critical role in promoting cell proliferation, survival, and tumor progression when dysregulated. While most Hippo pathway-targeting drugs focus on disrupting TE...
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| Main Authors: | Ji-Youn Lim, Eui-Hwan Choi, Yujeong Kim, Minseong Kim, Dongkyu Choi, Wantae Kim, Boksik Cha |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2025-12-01
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| Series: | Animal Cells and Systems |
| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/19768354.2025.2489389 |
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