Blood Pressure and Haematological Indices in Twelve Communities in Ashanti, Ghana
Hypertension is the most important risk factor for cardiovascular mortality and morbidity in Sub-Saharan Africa. In western populations, high haemoglobin levels are associated with raised BP unlike in Sub-Saharan Africa where there is a paucity of data. Our study examines the association between hae...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | International Journal of Hypertension |
| Online Access: | http://dx.doi.org/10.1155/2018/5952021 |
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| author | Jacob Plange-Rhule Sally M. Kerry John B. Eastwood Frank B. Micah Sampson Antwi Francesco P. Cappuccio |
| author_facet | Jacob Plange-Rhule Sally M. Kerry John B. Eastwood Frank B. Micah Sampson Antwi Francesco P. Cappuccio |
| author_sort | Jacob Plange-Rhule |
| collection | DOAJ |
| description | Hypertension is the most important risk factor for cardiovascular mortality and morbidity in Sub-Saharan Africa. In western populations, high haemoglobin levels are associated with raised BP unlike in Sub-Saharan Africa where there is a paucity of data. Our study examines the association between haematological indices with BP variables. Weight, height, BP, and whole blood indices of viscosity (Hb, haematocrit, RBC count, and MCV) were measured in 921 adults (340 men, 581 women; aged 40–75) in 12 communities in Ghana. Mean values for Hb (12.3 g/dl ± 1.7 SD), haematocrit (36.7%±5.2), RBC (4.10 million/μL ± 0.64), and MCV were lower than reference values used in Sub-Saharan Africa. Mean BMI was 21.1±4.1 indicating a lean population. Systolic BP increased by 1.0 mmHg (95% CI 0.5–1.5), p<0.001, for women and 0.5 (0.1–1.0), p=0.027, for men per unit increase in haematocrit. Similar relationships were found for Hb and RBC but not for MCV or platelets. The relationships were weaker when adjusted for BMI, 0.7 mmHg (0.2–1.2) in women and 0.5 (0.0–1.0) in men. Findings for diastolic BP were similar. Overall haematological indices were low. We have found a significant, positive relationship between BP, Hb, Haematocrit, and RBC count in our population. |
| format | Article |
| id | doaj-art-b7949335fb534adbac3799d2e54ba601 |
| institution | Kabale University |
| issn | 2090-0384 2090-0392 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Hypertension |
| spelling | doaj-art-b7949335fb534adbac3799d2e54ba6012025-02-03T06:42:18ZengWileyInternational Journal of Hypertension2090-03842090-03922018-01-01201810.1155/2018/59520215952021Blood Pressure and Haematological Indices in Twelve Communities in Ashanti, GhanaJacob Plange-Rhule0Sally M. Kerry1John B. Eastwood2Frank B. Micah3Sampson Antwi4Francesco P. Cappuccio5Division of Clinical Sciences, Renal Medicine, St George’s, University of London, Cranmer Terrace, London SW17 0RE, UKBlizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, 58 Turner Street, London E1 2AB, UKDivision of Clinical Sciences, Renal Medicine, St George’s, University of London, Cranmer Terrace, London SW17 0RE, UKDepartment of Medicine, Komfo Anokye Teaching Hospital, P.O. Box 1934, Kumasi, GhanaDepartment of Paediatrics, Komfo Anokye Teaching Hospital, P.O. Box 1934, Kumasi, GhanaDivision of Health Sciences, Warwick Medical School, University of Warwick, Gibbet Hill Road, Coventry CV4 &AL, UKHypertension is the most important risk factor for cardiovascular mortality and morbidity in Sub-Saharan Africa. In western populations, high haemoglobin levels are associated with raised BP unlike in Sub-Saharan Africa where there is a paucity of data. Our study examines the association between haematological indices with BP variables. Weight, height, BP, and whole blood indices of viscosity (Hb, haematocrit, RBC count, and MCV) were measured in 921 adults (340 men, 581 women; aged 40–75) in 12 communities in Ghana. Mean values for Hb (12.3 g/dl ± 1.7 SD), haematocrit (36.7%±5.2), RBC (4.10 million/μL ± 0.64), and MCV were lower than reference values used in Sub-Saharan Africa. Mean BMI was 21.1±4.1 indicating a lean population. Systolic BP increased by 1.0 mmHg (95% CI 0.5–1.5), p<0.001, for women and 0.5 (0.1–1.0), p=0.027, for men per unit increase in haematocrit. Similar relationships were found for Hb and RBC but not for MCV or platelets. The relationships were weaker when adjusted for BMI, 0.7 mmHg (0.2–1.2) in women and 0.5 (0.0–1.0) in men. Findings for diastolic BP were similar. Overall haematological indices were low. We have found a significant, positive relationship between BP, Hb, Haematocrit, and RBC count in our population.http://dx.doi.org/10.1155/2018/5952021 |
| spellingShingle | Jacob Plange-Rhule Sally M. Kerry John B. Eastwood Frank B. Micah Sampson Antwi Francesco P. Cappuccio Blood Pressure and Haematological Indices in Twelve Communities in Ashanti, Ghana International Journal of Hypertension |
| title | Blood Pressure and Haematological Indices in Twelve Communities in Ashanti, Ghana |
| title_full | Blood Pressure and Haematological Indices in Twelve Communities in Ashanti, Ghana |
| title_fullStr | Blood Pressure and Haematological Indices in Twelve Communities in Ashanti, Ghana |
| title_full_unstemmed | Blood Pressure and Haematological Indices in Twelve Communities in Ashanti, Ghana |
| title_short | Blood Pressure and Haematological Indices in Twelve Communities in Ashanti, Ghana |
| title_sort | blood pressure and haematological indices in twelve communities in ashanti ghana |
| url | http://dx.doi.org/10.1155/2018/5952021 |
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