Functional and internalizing disorders co-aggregate with cardiometabolic and immune-related diseases within families: a population-based cohort study

Functional and internalizing disorders co-aggregate with cardiometabolic and immune-related diseases within families: a population-based cohort study

Abstract Background Functional disorders share familial risk with internalizing disorders such as generalized anxiety disorder and depression, and are comorbid with cardiometabolic and immune-related diseases. We investigated whether functional and internalizing disorders co-aggregate with these dis...

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Bibliographic Details
Main Authors: Olivier D. Steen, Martje Bos, Sonja L. van Ockenburg, Yiling Zhou, Ilja M. Nolte, Harold Snieder, Kenneth Kendler, Judith G. M. Rosmalen, Hanna M. van Loo
Format: Article
Language:English
Published: BMC 2025-08-01
Series:BMC Medicine
Subjects:
Fibromyalgia
Myalgic encephalomyelitis/chronic fatigue syndrome
Irritable bowel syndrome
Aetiology
Familial co-aggregation
Cardiometabolic
Online Access:https://doi.org/10.1186/s12916-025-04293-7
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