Numerical simulations of a 3D fluid-structure interaction model for blood flow in an atherosclerotic artery
The inflammatory process of atherosclerosis leads to the formation of an atheromatous plaque in the intima of the blood vessel. The plaque rupture may result from the interaction between the blood and the plaque. In each cardiac cycle, blood interacts with the vessel, considered as a compliant nonli...
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AIMS Press
2017-01-01
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| Series: | Mathematical Biosciences and Engineering |
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| Online Access: | https://www.aimspress.com/article/doi/10.3934/mbe.2017012 |
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| author | Oualid Kafi Nader El Khatib Jorge Tiago Adélia Sequeira |
| author_facet | Oualid Kafi Nader El Khatib Jorge Tiago Adélia Sequeira |
| author_sort | Oualid Kafi |
| collection | DOAJ |
| description | The inflammatory process of atherosclerosis leads to the formation of an atheromatous plaque in the intima of the blood vessel. The plaque rupture may result from the interaction between the blood and the plaque. In each cardiac cycle, blood interacts with the vessel, considered as a compliant nonlinear hyperelastic. A three dimensional idealized fluid-structure interaction (FSI) model is constructed to perform the blood-plaque and blood-vessel wall interaction studies. An absorbing boundary condition (BC) is imposed directly on the outflow in order to cope with the spurious reflexions due to the truncation of the computational domain. The difference between the Newtonian and non-Newtonian effects is highlighted. It is shown that the von Mises and wall shear stresses are significantly affected according to the rigidity of the wall. The numerical results have shown that the risk of plaque rupture is higher in the case of a moving wall, while in the case of a fixed wall the risk of progression of the atheromatous plaque is higher. |
| format | Article |
| id | doaj-art-b7637834931743a1afe28b12957a22fe |
| institution | Kabale University |
| issn | 1551-0018 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | AIMS Press |
| record_format | Article |
| series | Mathematical Biosciences and Engineering |
| spelling | doaj-art-b7637834931743a1afe28b12957a22fe2025-01-24T02:39:32ZengAIMS PressMathematical Biosciences and Engineering1551-00182017-01-0114117919310.3934/mbe.2017012Numerical simulations of a 3D fluid-structure interaction model for blood flow in an atherosclerotic arteryOualid Kafi0Nader El Khatib1Jorge Tiago2Adélia Sequeira3Dept. Math., IST, Univ. Lisboa and CEMAT, Av. Rovisco Pais, 1049-001, Lisboa, PortugalDept. of CS. and Math., LAU, P-36, Byblos, LebanonDept. Math., IST, Univ. Lisboa and CEMAT, Av. Rovisco Pais, 1049-001, Lisboa, PortugalDept. Math., IST, Univ. Lisboa and CEMAT, Av. Rovisco Pais, 1049-001, Lisboa, PortugalThe inflammatory process of atherosclerosis leads to the formation of an atheromatous plaque in the intima of the blood vessel. The plaque rupture may result from the interaction between the blood and the plaque. In each cardiac cycle, blood interacts with the vessel, considered as a compliant nonlinear hyperelastic. A three dimensional idealized fluid-structure interaction (FSI) model is constructed to perform the blood-plaque and blood-vessel wall interaction studies. An absorbing boundary condition (BC) is imposed directly on the outflow in order to cope with the spurious reflexions due to the truncation of the computational domain. The difference between the Newtonian and non-Newtonian effects is highlighted. It is shown that the von Mises and wall shear stresses are significantly affected according to the rigidity of the wall. The numerical results have shown that the risk of plaque rupture is higher in the case of a moving wall, while in the case of a fixed wall the risk of progression of the atheromatous plaque is higher.https://www.aimspress.com/article/doi/10.3934/mbe.2017012atherosclerosisblood flownon-newtionian fluidfluid-structure interactionwall shear stressnonlinear hyperelastic structure |
| spellingShingle | Oualid Kafi Nader El Khatib Jorge Tiago Adélia Sequeira Numerical simulations of a 3D fluid-structure interaction model for blood flow in an atherosclerotic artery Mathematical Biosciences and Engineering atherosclerosis blood flow non-newtionian fluid fluid-structure interaction wall shear stress nonlinear hyperelastic structure |
| title | Numerical simulations of a 3D fluid-structure interaction model for blood flow in an atherosclerotic artery |
| title_full | Numerical simulations of a 3D fluid-structure interaction model for blood flow in an atherosclerotic artery |
| title_fullStr | Numerical simulations of a 3D fluid-structure interaction model for blood flow in an atherosclerotic artery |
| title_full_unstemmed | Numerical simulations of a 3D fluid-structure interaction model for blood flow in an atherosclerotic artery |
| title_short | Numerical simulations of a 3D fluid-structure interaction model for blood flow in an atherosclerotic artery |
| title_sort | numerical simulations of a 3d fluid structure interaction model for blood flow in an atherosclerotic artery |
| topic | atherosclerosis blood flow non-newtionian fluid fluid-structure interaction wall shear stress nonlinear hyperelastic structure |
| url | https://www.aimspress.com/article/doi/10.3934/mbe.2017012 |
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