Sarcoidosis Associated with Oxaliplatin-Based Chemotherapy for Colorectal Cancer
Acute lung injury occasionally occurs after chemotherapy, but pulmonary toxicities by oxaliplatin-based chemotherapy have rarely been identified. A 76-year-old female with rectosigmoid colon cancer presented with ongoing dyspnea after the eighth cycle of standard chemotherapy (5-fluorouracil, sodium...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2014-01-01
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| Series: | Case Reports in Oncological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2014/203027 |
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| _version_ | 1832555390616731648 |
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| author | Ji Hoon Choi Jung A. Shin Hye Kyeong Park Su Young Kim Hoon Jung Sung-Soon Lee Hye Ran Lee Hyeon-Kyoung Koo |
| author_facet | Ji Hoon Choi Jung A. Shin Hye Kyeong Park Su Young Kim Hoon Jung Sung-Soon Lee Hye Ran Lee Hyeon-Kyoung Koo |
| author_sort | Ji Hoon Choi |
| collection | DOAJ |
| description | Acute lung injury occasionally occurs after chemotherapy, but pulmonary toxicities by oxaliplatin-based chemotherapy have rarely been identified. A 76-year-old female with rectosigmoid colon cancer presented with ongoing dyspnea after the eighth cycle of standard chemotherapy (5-fluorouracil, sodium folinic acid, and oxaliplatin: FOLFOX). Nodular consolidation progressed despite antibiotics and BAL fluid analysis was compatible with the diagnosis of sarcoidosis. Corticosteroid therapy rapidly improved the symptoms and radiographic findings. We report this first case of secondary sarcoidosis related to FOLFOX therapy with review of references. |
| format | Article |
| id | doaj-art-b75baf51d692443495fd70b9b05b5d58 |
| institution | Kabale University |
| issn | 2090-6706 2090-6714 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Oncological Medicine |
| spelling | doaj-art-b75baf51d692443495fd70b9b05b5d582025-02-03T05:48:24ZengWileyCase Reports in Oncological Medicine2090-67062090-67142014-01-01201410.1155/2014/203027203027Sarcoidosis Associated with Oxaliplatin-Based Chemotherapy for Colorectal CancerJi Hoon Choi0Jung A. Shin1Hye Kyeong Park2Su Young Kim3Hoon Jung4Sung-Soon Lee5Hye Ran Lee6Hyeon-Kyoung Koo7Department of Internal Medicine, Ilsan Paik Hospital, Inje University College of Medicine, Daehwa-dong, Ilsanseo-gu, Goyang-si, Gyeonggi-do 2240, Republic of KoreaDepartment of Internal Medicine, Ilsan Paik Hospital, Inje University College of Medicine, Daehwa-dong, Ilsanseo-gu, Goyang-si, Gyeonggi-do 2240, Republic of KoreaDepartment of Internal Medicine, Ilsan Paik Hospital, Inje University College of Medicine, Daehwa-dong, Ilsanseo-gu, Goyang-si, Gyeonggi-do 2240, Republic of KoreaDepartment of Radiology, Ilsan Paik Hospital, Inje University College of Medicine, Daehwa-dong, Ilsanseo-gu, Goyang-si, Gyeonggi-do 2240, Republic of KoreaDepartment of Internal Medicine, Ilsan Paik Hospital, Inje University College of Medicine, Daehwa-dong, Ilsanseo-gu, Goyang-si, Gyeonggi-do 2240, Republic of KoreaDepartment of Internal Medicine, Ilsan Paik Hospital, Inje University College of Medicine, Daehwa-dong, Ilsanseo-gu, Goyang-si, Gyeonggi-do 2240, Republic of KoreaDepartment of Internal Medicine, Ilsan Paik Hospital, Inje University College of Medicine, Daehwa-dong, Ilsanseo-gu, Goyang-si, Gyeonggi-do 2240, Republic of KoreaDepartment of Internal Medicine, Ilsan Paik Hospital, Inje University College of Medicine, Daehwa-dong, Ilsanseo-gu, Goyang-si, Gyeonggi-do 2240, Republic of KoreaAcute lung injury occasionally occurs after chemotherapy, but pulmonary toxicities by oxaliplatin-based chemotherapy have rarely been identified. A 76-year-old female with rectosigmoid colon cancer presented with ongoing dyspnea after the eighth cycle of standard chemotherapy (5-fluorouracil, sodium folinic acid, and oxaliplatin: FOLFOX). Nodular consolidation progressed despite antibiotics and BAL fluid analysis was compatible with the diagnosis of sarcoidosis. Corticosteroid therapy rapidly improved the symptoms and radiographic findings. We report this first case of secondary sarcoidosis related to FOLFOX therapy with review of references.http://dx.doi.org/10.1155/2014/203027 |
| spellingShingle | Ji Hoon Choi Jung A. Shin Hye Kyeong Park Su Young Kim Hoon Jung Sung-Soon Lee Hye Ran Lee Hyeon-Kyoung Koo Sarcoidosis Associated with Oxaliplatin-Based Chemotherapy for Colorectal Cancer Case Reports in Oncological Medicine |
| title | Sarcoidosis Associated with Oxaliplatin-Based Chemotherapy for Colorectal Cancer |
| title_full | Sarcoidosis Associated with Oxaliplatin-Based Chemotherapy for Colorectal Cancer |
| title_fullStr | Sarcoidosis Associated with Oxaliplatin-Based Chemotherapy for Colorectal Cancer |
| title_full_unstemmed | Sarcoidosis Associated with Oxaliplatin-Based Chemotherapy for Colorectal Cancer |
| title_short | Sarcoidosis Associated with Oxaliplatin-Based Chemotherapy for Colorectal Cancer |
| title_sort | sarcoidosis associated with oxaliplatin based chemotherapy for colorectal cancer |
| url | http://dx.doi.org/10.1155/2014/203027 |
| work_keys_str_mv | AT jihoonchoi sarcoidosisassociatedwithoxaliplatinbasedchemotherapyforcolorectalcancer AT jungashin sarcoidosisassociatedwithoxaliplatinbasedchemotherapyforcolorectalcancer AT hyekyeongpark sarcoidosisassociatedwithoxaliplatinbasedchemotherapyforcolorectalcancer AT suyoungkim sarcoidosisassociatedwithoxaliplatinbasedchemotherapyforcolorectalcancer AT hoonjung sarcoidosisassociatedwithoxaliplatinbasedchemotherapyforcolorectalcancer AT sungsoonlee sarcoidosisassociatedwithoxaliplatinbasedchemotherapyforcolorectalcancer AT hyeranlee sarcoidosisassociatedwithoxaliplatinbasedchemotherapyforcolorectalcancer AT hyeonkyoungkoo sarcoidosisassociatedwithoxaliplatinbasedchemotherapyforcolorectalcancer |