Intralipid Therapy for Inadvertent Peripheral Nervous System Blockade Resulting from Local Anesthetic Overdose
Although local anesthetics have an acceptable safety profile, significant morbidity and mortality have been associated with their use. Inadvertent intravascular injection of local anesthetics and/or the use of excessive doses have been the most frequent causes of local anesthetic systemic toxicity (...
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Case Reports in Anesthesiology |
| Online Access: | http://dx.doi.org/10.1155/2015/486543 |
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| _version_ | 1832560618459103232 |
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| author | Ihab Kamel Gaurav Trehan Rodger Barnette |
| author_facet | Ihab Kamel Gaurav Trehan Rodger Barnette |
| author_sort | Ihab Kamel |
| collection | DOAJ |
| description | Although local anesthetics have an acceptable safety profile, significant morbidity and mortality have been associated with their use. Inadvertent intravascular injection of local anesthetics and/or the use of excessive doses have been the most frequent causes of local anesthetic systemic toxicity (LAST). Furthermore, excessive doses of local anesthetics injected locally into the tissues may lead to inadvertent peripheral nerve infiltration and blockade. Successful treatment of LAST with intralipid has been reported. We describe a case of local anesthetic overdose that resulted in LAST and in unintentional blockade of peripheral nerves of the lower extremity; both effects completely resolved with administration of intralipid. |
| format | Article |
| id | doaj-art-b75683bfac9c4d0684cd0249abf63966 |
| institution | Kabale University |
| issn | 2090-6382 2090-6390 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Anesthesiology |
| spelling | doaj-art-b75683bfac9c4d0684cd0249abf639662025-02-03T01:27:13ZengWileyCase Reports in Anesthesiology2090-63822090-63902015-01-01201510.1155/2015/486543486543Intralipid Therapy for Inadvertent Peripheral Nervous System Blockade Resulting from Local Anesthetic OverdoseIhab Kamel0Gaurav Trehan1Rodger Barnette2Temple University School of Medicine, 3401 N. Broad Street, 3rd Floor Outpatient Building, Zone B, Philadelphia, PA 19140, USATemple University School of Medicine, 3401 N. Broad Street, 3rd Floor Outpatient Building, Zone B, Philadelphia, PA 19140, USATemple University School of Medicine, 3401 N. Broad Street, 3rd Floor Outpatient Building, Zone B, Philadelphia, PA 19140, USAAlthough local anesthetics have an acceptable safety profile, significant morbidity and mortality have been associated with their use. Inadvertent intravascular injection of local anesthetics and/or the use of excessive doses have been the most frequent causes of local anesthetic systemic toxicity (LAST). Furthermore, excessive doses of local anesthetics injected locally into the tissues may lead to inadvertent peripheral nerve infiltration and blockade. Successful treatment of LAST with intralipid has been reported. We describe a case of local anesthetic overdose that resulted in LAST and in unintentional blockade of peripheral nerves of the lower extremity; both effects completely resolved with administration of intralipid.http://dx.doi.org/10.1155/2015/486543 |
| spellingShingle | Ihab Kamel Gaurav Trehan Rodger Barnette Intralipid Therapy for Inadvertent Peripheral Nervous System Blockade Resulting from Local Anesthetic Overdose Case Reports in Anesthesiology |
| title | Intralipid Therapy for Inadvertent Peripheral Nervous System Blockade Resulting from Local Anesthetic Overdose |
| title_full | Intralipid Therapy for Inadvertent Peripheral Nervous System Blockade Resulting from Local Anesthetic Overdose |
| title_fullStr | Intralipid Therapy for Inadvertent Peripheral Nervous System Blockade Resulting from Local Anesthetic Overdose |
| title_full_unstemmed | Intralipid Therapy for Inadvertent Peripheral Nervous System Blockade Resulting from Local Anesthetic Overdose |
| title_short | Intralipid Therapy for Inadvertent Peripheral Nervous System Blockade Resulting from Local Anesthetic Overdose |
| title_sort | intralipid therapy for inadvertent peripheral nervous system blockade resulting from local anesthetic overdose |
| url | http://dx.doi.org/10.1155/2015/486543 |
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