Age Dependent Switching Role of Cyclin D1 in Breast Cancer

Background: Cyclin D1 gene (CCND1) plays pivotal roles in the development of several human cancers, including breast cancer, functioning as an oncogene. The aim of this study was to better understand the molecular dynamics of ductal carcinomas with regard to proliferation and the ageing process.

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Main Authors: Carmela Rinaldi, Natalia Maria Malara, Rosalia D’Angelo, Antonina Sidoti, Attilio Leotta, Santo Lio, Basilio Caparello, Alessia Ruggeri, Vincenzo Mollace, Aldo Amato
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Analytical Cellular Pathology
Online Access:http://dx.doi.org/10.3233/ACP-2011-0052
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author Carmela Rinaldi
Natalia Maria Malara
Rosalia D’Angelo
Antonina Sidoti
Attilio Leotta
Santo Lio
Basilio Caparello
Alessia Ruggeri
Vincenzo Mollace
Aldo Amato
author_facet Carmela Rinaldi
Natalia Maria Malara
Rosalia D’Angelo
Antonina Sidoti
Attilio Leotta
Santo Lio
Basilio Caparello
Alessia Ruggeri
Vincenzo Mollace
Aldo Amato
author_sort Carmela Rinaldi
collection DOAJ
description Background: Cyclin D1 gene (CCND1) plays pivotal roles in the development of several human cancers, including breast cancer, functioning as an oncogene. The aim of this study was to better understand the molecular dynamics of ductal carcinomas with regard to proliferation and the ageing process.
format Article
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institution Kabale University
issn 2210-7177
2210-7185
language English
publishDate 2012-01-01
publisher Wiley
record_format Article
series Analytical Cellular Pathology
spelling doaj-art-b74a1f0afee642c887637bb12e45f2aa2025-02-03T05:52:46ZengWileyAnalytical Cellular Pathology2210-71772210-71852012-01-0135317918510.3233/ACP-2011-0052Age Dependent Switching Role of Cyclin D1 in Breast CancerCarmela Rinaldi0Natalia Maria Malara1Rosalia D’Angelo2Antonina Sidoti3Attilio Leotta4Santo Lio5Basilio Caparello6Alessia Ruggeri7Vincenzo Mollace8Aldo Amato9Faculty of Medicine, Department of Biomorphology and Biotechnologies, Division of Biology and Genetics, University of Messina, Messina, ItalyLaboratory of Toxicology, Faculty of Pharmacy, Department of Pharmaceutical Science, University of Magna Graecia, Catanzaro, ItalyFaculty of Medicine, Department of Biomorphology and Biotechnologies, Division of Biology and Genetics, University of Messina, Messina, ItalyFaculty of Medicine, Department of Biomorphology and Biotechnologies, Division of Biology and Genetics, University of Messina, Messina, ItalyDepartment of Pathology, Lamezia Terme Hospital, Lamezia Terme CZ, ItalyDepartment of Pathology, Lamezia Terme Hospital, Lamezia Terme CZ, ItalyDepartment of Pathology, Lamezia Terme Hospital, Lamezia Terme CZ, ItalyFaculty of Medicine, Department of Biomorphology and Biotechnologies, Division of Biology and Genetics, University of Messina, Messina, ItalyLaboratory of Toxicology, Faculty of Pharmacy, Department of Pharmaceutical Science, University of Magna Graecia, Catanzaro, ItalyFaculty of Medicine, Department of Biomorphology and Biotechnologies, Division of Biology and Genetics, University of Messina, Messina, ItalyBackground: Cyclin D1 gene (CCND1) plays pivotal roles in the development of several human cancers, including breast cancer, functioning as an oncogene. The aim of this study was to better understand the molecular dynamics of ductal carcinomas with regard to proliferation and the ageing process.http://dx.doi.org/10.3233/ACP-2011-0052
spellingShingle Carmela Rinaldi
Natalia Maria Malara
Rosalia D’Angelo
Antonina Sidoti
Attilio Leotta
Santo Lio
Basilio Caparello
Alessia Ruggeri
Vincenzo Mollace
Aldo Amato
Age Dependent Switching Role of Cyclin D1 in Breast Cancer
Analytical Cellular Pathology
title Age Dependent Switching Role of Cyclin D1 in Breast Cancer
title_full Age Dependent Switching Role of Cyclin D1 in Breast Cancer
title_fullStr Age Dependent Switching Role of Cyclin D1 in Breast Cancer
title_full_unstemmed Age Dependent Switching Role of Cyclin D1 in Breast Cancer
title_short Age Dependent Switching Role of Cyclin D1 in Breast Cancer
title_sort age dependent switching role of cyclin d1 in breast cancer
url http://dx.doi.org/10.3233/ACP-2011-0052
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