A Rare Tumor with a Very Rare Initial Presentation: Thymic Carcinoma as Bone Marrow Metastasis

Tumors of thymus gland are rare and account for 0.2% to 1.5% of all the neoplasms. They constitute a heterogeneous group that has an unknown etiology and a complex as well as varied biology. This has led to difficulty in their histological classification and in predicting their prognostic and surviv...

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Main Authors: Sonam Sharma, Leelavathi Dawson
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Case Reports in Pathology
Online Access:http://dx.doi.org/10.1155/2017/6497376
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author Sonam Sharma
Leelavathi Dawson
author_facet Sonam Sharma
Leelavathi Dawson
author_sort Sonam Sharma
collection DOAJ
description Tumors of thymus gland are rare and account for 0.2% to 1.5% of all the neoplasms. They constitute a heterogeneous group that has an unknown etiology and a complex as well as varied biology. This has led to difficulty in their histological classification and in predicting their prognostic and survival markers. Among them, thymic carcinoma is the most aggressive thymic epithelial tumor exhibiting cytological malignant features and a diversity of clinicopathological characteristics that can cause diagnostic dilemmas, misdiagnosis, and therapeutic challenge. We herein describe a case of a 60-year-old man who while undergoing evaluation for the cause of pancytopenia was discovered having bone marrow metastasis from an asymptomatic thymic carcinoma. Bone marrow metastasis is an extremely rare initial presentation of thymic carcinoma with only few cases reported in the literature.
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series Case Reports in Pathology
spelling doaj-art-b73485abd2444f4096a1dbcfbf74aec42025-02-03T05:59:13ZengWileyCase Reports in Pathology2090-67812090-679X2017-01-01201710.1155/2017/64973766497376A Rare Tumor with a Very Rare Initial Presentation: Thymic Carcinoma as Bone Marrow MetastasisSonam Sharma0Leelavathi Dawson1Department of Pathology, Vardhman Mahavir Medical College & Safdarjung Hospital, New Delhi, IndiaDepartment of Pathology, Vardhman Mahavir Medical College & Safdarjung Hospital, New Delhi, IndiaTumors of thymus gland are rare and account for 0.2% to 1.5% of all the neoplasms. They constitute a heterogeneous group that has an unknown etiology and a complex as well as varied biology. This has led to difficulty in their histological classification and in predicting their prognostic and survival markers. Among them, thymic carcinoma is the most aggressive thymic epithelial tumor exhibiting cytological malignant features and a diversity of clinicopathological characteristics that can cause diagnostic dilemmas, misdiagnosis, and therapeutic challenge. We herein describe a case of a 60-year-old man who while undergoing evaluation for the cause of pancytopenia was discovered having bone marrow metastasis from an asymptomatic thymic carcinoma. Bone marrow metastasis is an extremely rare initial presentation of thymic carcinoma with only few cases reported in the literature.http://dx.doi.org/10.1155/2017/6497376
spellingShingle Sonam Sharma
Leelavathi Dawson
A Rare Tumor with a Very Rare Initial Presentation: Thymic Carcinoma as Bone Marrow Metastasis
Case Reports in Pathology
title A Rare Tumor with a Very Rare Initial Presentation: Thymic Carcinoma as Bone Marrow Metastasis
title_full A Rare Tumor with a Very Rare Initial Presentation: Thymic Carcinoma as Bone Marrow Metastasis
title_fullStr A Rare Tumor with a Very Rare Initial Presentation: Thymic Carcinoma as Bone Marrow Metastasis
title_full_unstemmed A Rare Tumor with a Very Rare Initial Presentation: Thymic Carcinoma as Bone Marrow Metastasis
title_short A Rare Tumor with a Very Rare Initial Presentation: Thymic Carcinoma as Bone Marrow Metastasis
title_sort rare tumor with a very rare initial presentation thymic carcinoma as bone marrow metastasis
url http://dx.doi.org/10.1155/2017/6497376
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