The synthesis of chitosan-sodium tripolyphosphate nanoparticles for delivery of Ocimum africanum extract
The aim of the present work is to obtain Ocimum africanum extract nanoparticles (OaE-NPs) that have been crosslinked via ionic gelation with chitosan (chi) and sodium tripolyphosphate (TPP). Nanoencapsulation will enable investigation of the morphology profile and size of OaE-NPs. The OaE-NPs produc...
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| Format: | Article |
| Language: | English |
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EDP Sciences
2025-01-01
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| Series: | BIO Web of Conferences |
| Online Access: | https://www.bio-conferences.org/articles/bioconf/pdf/2025/05/bioconf_icgrc2025_04003.pdf |
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| author | Rahayu Sri Widyarti Sri Soewondo Aris Prasetyaningrum Dian Islami Umarudin Umarudin Atho’illah Mochammad Fitri |
| author_facet | Rahayu Sri Widyarti Sri Soewondo Aris Prasetyaningrum Dian Islami Umarudin Umarudin Atho’illah Mochammad Fitri |
| author_sort | Rahayu Sri |
| collection | DOAJ |
| description | The aim of the present work is to obtain Ocimum africanum extract nanoparticles (OaE-NPs) that have been crosslinked via ionic gelation with chitosan (chi) and sodium tripolyphosphate (TPP). Nanoencapsulation will enable investigation of the morphology profile and size of OaE-NPs. The OaE-NPs produced via ionic gelation exhibited a 6.4 nm in size and a low polydispersity index (PDI) of 0.177. Additionally, SEM observation revealed that the surface shape of OaE-NPs was a loose aggregate with an uneven surface. These findings provide a simple and reliable approach for generating nanoparticles from O. africanum coated with chitosan/TPP. |
| format | Article |
| id | doaj-art-b71f0ac3cca54835883e8050cc689a6c |
| institution | Kabale University |
| issn | 2117-4458 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | EDP Sciences |
| record_format | Article |
| series | BIO Web of Conferences |
| spelling | doaj-art-b71f0ac3cca54835883e8050cc689a6c2025-02-05T10:43:08ZengEDP SciencesBIO Web of Conferences2117-44582025-01-011540400310.1051/bioconf/202515404003bioconf_icgrc2025_04003The synthesis of chitosan-sodium tripolyphosphate nanoparticles for delivery of Ocimum africanum extractRahayu Sri0Widyarti Sri1Soewondo Aris2Prasetyaningrum Dian Islami3Umarudin Umarudin4Atho’illah Mochammad Fitri5Department of Biology, Faculty of Mathematics and Natural Sciences, Brawijaya UniversityDepartment of Biology, Faculty of Mathematics and Natural Sciences, Brawijaya UniversityDepartment of Biology, Faculty of Mathematics and Natural Sciences, Brawijaya UniversityDepartment of Socio-Economic Agriculture, Faculty of Agriculture, Brawijaya UniversityProgram Study of Pharmacy, Pharmacy Academy of SurabayaDoctoral program of Biology, Department of Biology, Faculty of Mathematics and Natural Sciences, Brawijaya UniversityThe aim of the present work is to obtain Ocimum africanum extract nanoparticles (OaE-NPs) that have been crosslinked via ionic gelation with chitosan (chi) and sodium tripolyphosphate (TPP). Nanoencapsulation will enable investigation of the morphology profile and size of OaE-NPs. The OaE-NPs produced via ionic gelation exhibited a 6.4 nm in size and a low polydispersity index (PDI) of 0.177. Additionally, SEM observation revealed that the surface shape of OaE-NPs was a loose aggregate with an uneven surface. These findings provide a simple and reliable approach for generating nanoparticles from O. africanum coated with chitosan/TPP.https://www.bio-conferences.org/articles/bioconf/pdf/2025/05/bioconf_icgrc2025_04003.pdf |
| spellingShingle | Rahayu Sri Widyarti Sri Soewondo Aris Prasetyaningrum Dian Islami Umarudin Umarudin Atho’illah Mochammad Fitri The synthesis of chitosan-sodium tripolyphosphate nanoparticles for delivery of Ocimum africanum extract BIO Web of Conferences |
| title | The synthesis of chitosan-sodium tripolyphosphate nanoparticles for delivery of Ocimum africanum extract |
| title_full | The synthesis of chitosan-sodium tripolyphosphate nanoparticles for delivery of Ocimum africanum extract |
| title_fullStr | The synthesis of chitosan-sodium tripolyphosphate nanoparticles for delivery of Ocimum africanum extract |
| title_full_unstemmed | The synthesis of chitosan-sodium tripolyphosphate nanoparticles for delivery of Ocimum africanum extract |
| title_short | The synthesis of chitosan-sodium tripolyphosphate nanoparticles for delivery of Ocimum africanum extract |
| title_sort | synthesis of chitosan sodium tripolyphosphate nanoparticles for delivery of ocimum africanum extract |
| url | https://www.bio-conferences.org/articles/bioconf/pdf/2025/05/bioconf_icgrc2025_04003.pdf |
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