5-ASA Suppositories in Hemorrhoidal Disease
Forty patients with active hemorrhoidal disease were entered into this double-blind trial, 20 of whom were randomized to treatment with 5-aminosalicylic acid (5-ASA) (500 mg) suppositories. Clinical and sigmoidoscopic assessment was carried out before the start of the trial and after two weeks of tr...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
1992-01-01
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| Series: | Canadian Journal of Gastroenterology |
| Online Access: | http://dx.doi.org/10.1155/1992/715270 |
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| _version_ | 1832563588760338432 |
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| author | P Gionchetti M Campieri A Belluzzi C Brignola M Miglioli L Barbara |
| author_facet | P Gionchetti M Campieri A Belluzzi C Brignola M Miglioli L Barbara |
| author_sort | P Gionchetti |
| collection | DOAJ |
| description | Forty patients with active hemorrhoidal disease were entered into this double-blind trial, 20 of whom were randomized to treatment with 5-aminosalicylic acid (5-ASA) (500 mg) suppositories. Clinical and sigmoidoscopic assessment was carried out before the start of the trial and after two weeks of treatment. At the end of the study, 5-ASA suppositories showed results superior to those of placebo for all parameters evaluated (P<0.01). There were no adverse events reported related to the use of suppositories. 5-ASA suppositories are a valid therapeutic approach for hemorrhoidal disease as it reduces the intensity of all symptoms and significantly decreases congestion of the hemorrhoidal plexus. |
| format | Article |
| id | doaj-art-b6fa4e5ca0a44a5ebc62ff9d3e58caf8 |
| institution | Kabale University |
| issn | 0835-7900 |
| language | English |
| publishDate | 1992-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Gastroenterology |
| spelling | doaj-art-b6fa4e5ca0a44a5ebc62ff9d3e58caf82025-02-03T01:13:13ZengWileyCanadian Journal of Gastroenterology0835-79001992-01-0161182010.1155/1992/7152705-ASA Suppositories in Hemorrhoidal DiseaseP Gionchetti0M Campieri1A Belluzzi2C Brignola3M Miglioli4L Barbara5Policlinico S Orsola–Istituto di Clinica Medica e Gastroenterologia–Via Massarenti, 9-40100 Bologna, ItalyPoliclinico S Orsola–Istituto di Clinica Medica e Gastroenterologia–Via Massarenti, 9-40100 Bologna, ItalyPoliclinico S Orsola–Istituto di Clinica Medica e Gastroenterologia–Via Massarenti, 9-40100 Bologna, ItalyPoliclinico S Orsola–Istituto di Clinica Medica e Gastroenterologia–Via Massarenti, 9-40100 Bologna, ItalyPoliclinico S Orsola–Istituto di Clinica Medica e Gastroenterologia–Via Massarenti, 9-40100 Bologna, ItalyPoliclinico S Orsola–Istituto di Clinica Medica e Gastroenterologia–Via Massarenti, 9-40100 Bologna, ItalyForty patients with active hemorrhoidal disease were entered into this double-blind trial, 20 of whom were randomized to treatment with 5-aminosalicylic acid (5-ASA) (500 mg) suppositories. Clinical and sigmoidoscopic assessment was carried out before the start of the trial and after two weeks of treatment. At the end of the study, 5-ASA suppositories showed results superior to those of placebo for all parameters evaluated (P<0.01). There were no adverse events reported related to the use of suppositories. 5-ASA suppositories are a valid therapeutic approach for hemorrhoidal disease as it reduces the intensity of all symptoms and significantly decreases congestion of the hemorrhoidal plexus.http://dx.doi.org/10.1155/1992/715270 |
| spellingShingle | P Gionchetti M Campieri A Belluzzi C Brignola M Miglioli L Barbara 5-ASA Suppositories in Hemorrhoidal Disease Canadian Journal of Gastroenterology |
| title | 5-ASA Suppositories in Hemorrhoidal Disease |
| title_full | 5-ASA Suppositories in Hemorrhoidal Disease |
| title_fullStr | 5-ASA Suppositories in Hemorrhoidal Disease |
| title_full_unstemmed | 5-ASA Suppositories in Hemorrhoidal Disease |
| title_short | 5-ASA Suppositories in Hemorrhoidal Disease |
| title_sort | 5 asa suppositories in hemorrhoidal disease |
| url | http://dx.doi.org/10.1155/1992/715270 |
| work_keys_str_mv | AT pgionchetti 5asasuppositoriesinhemorrhoidaldisease AT mcampieri 5asasuppositoriesinhemorrhoidaldisease AT abelluzzi 5asasuppositoriesinhemorrhoidaldisease AT cbrignola 5asasuppositoriesinhemorrhoidaldisease AT mmiglioli 5asasuppositoriesinhemorrhoidaldisease AT lbarbara 5asasuppositoriesinhemorrhoidaldisease |