An overview of the human immune system and the role of interferon regulatory factors (IRFs)

The immune system consists of a dynamic network of cells, proteins, tissues, and organs that communicate to provide adequate defense responses against pathogenic agents. The immune system divide into the non-specific (innate) and the specific (adaptive) components, where the interactions between th...

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Main Authors: Ashwinder Kaur, Chee-Mun Fang
Format: Article
Language:English
Published: HH Publisher 2020-11-01
Series:Progress in Microbes and Molecular Biology
Online Access:https://journals.hh-publisher.com/index.php/pmmb/article/view/338
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author Ashwinder Kaur
Chee-Mun Fang
author_facet Ashwinder Kaur
Chee-Mun Fang
author_sort Ashwinder Kaur
collection DOAJ
description The immune system consists of a dynamic network of cells, proteins, tissues, and organs that communicate to provide adequate defense responses against pathogenic agents. The immune system divide into the non-specific (innate) and the specific (adaptive) components, where the interactions between these two arms are intricately regulated. To deploy effective immune responses, immune systems comprise various cells and molecules that communicate with each other via signaling pathways coordinated by gene regulatory networks. The interferon regulatory factors (IRFs) are critical regulators of both the immune system’s development and activation of different cells. To better understand the essential components of the normal immune system, this review essentially aims to cover the current knowledge of individual components of the immune system and the important role of IRFs in regulating the immune system.
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publishDate 2020-11-01
publisher HH Publisher
record_format Article
series Progress in Microbes and Molecular Biology
spelling doaj-art-b6f8a3875d0647dba9b9a76d23b80b2b2025-02-04T08:36:59ZengHH PublisherProgress in Microbes and Molecular Biology2637-10492020-11-013110.36877/pmmb.a0000129An overview of the human immune system and the role of interferon regulatory factors (IRFs)Ashwinder KaurChee-Mun Fang The immune system consists of a dynamic network of cells, proteins, tissues, and organs that communicate to provide adequate defense responses against pathogenic agents. The immune system divide into the non-specific (innate) and the specific (adaptive) components, where the interactions between these two arms are intricately regulated. To deploy effective immune responses, immune systems comprise various cells and molecules that communicate with each other via signaling pathways coordinated by gene regulatory networks. The interferon regulatory factors (IRFs) are critical regulators of both the immune system’s development and activation of different cells. To better understand the essential components of the normal immune system, this review essentially aims to cover the current knowledge of individual components of the immune system and the important role of IRFs in regulating the immune system. https://journals.hh-publisher.com/index.php/pmmb/article/view/338
spellingShingle Ashwinder Kaur
Chee-Mun Fang
An overview of the human immune system and the role of interferon regulatory factors (IRFs)
Progress in Microbes and Molecular Biology
title An overview of the human immune system and the role of interferon regulatory factors (IRFs)
title_full An overview of the human immune system and the role of interferon regulatory factors (IRFs)
title_fullStr An overview of the human immune system and the role of interferon regulatory factors (IRFs)
title_full_unstemmed An overview of the human immune system and the role of interferon regulatory factors (IRFs)
title_short An overview of the human immune system and the role of interferon regulatory factors (IRFs)
title_sort overview of the human immune system and the role of interferon regulatory factors irfs
url https://journals.hh-publisher.com/index.php/pmmb/article/view/338
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