The Effects of Local Administration of Aminophylline on Transureteral Lithotripsy

Introduction. Urinary stone is a common cause of urinary tract disease. Stone excretion using ureteroscope is effective in inferior ureter. The aim of this study was to investigate the effects of aminophylline on ureteral spasm during ureteroscopy in acute phase of renal colic. Methods. In this doub...

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Main Authors: Ayyoub Barzegarnezhad, Abolfazl Firouzian, Seyed Abdollah Emadi, Nadali Mousanejad, Roksana Bakhshali
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Advances in Urology
Online Access:http://dx.doi.org/10.1155/2012/727843
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author Ayyoub Barzegarnezhad
Abolfazl Firouzian
Seyed Abdollah Emadi
Nadali Mousanejad
Roksana Bakhshali
author_facet Ayyoub Barzegarnezhad
Abolfazl Firouzian
Seyed Abdollah Emadi
Nadali Mousanejad
Roksana Bakhshali
author_sort Ayyoub Barzegarnezhad
collection DOAJ
description Introduction. Urinary stone is a common cause of urinary tract disease. Stone excretion using ureteroscope is effective in inferior ureter. The aim of this study was to investigate the effects of aminophylline on ureteral spasm during ureteroscopy in acute phase of renal colic. Methods. In this double-blind randomized clinical trial, 120 patients with ureteral stones were enrolled and randomized into two groups. The bladder was drained and then received a 150 mL irrigation solution. Irrigation solution was saline and saline plus 10 mL aminophylline at 250 mg dose for control and case groups, respectively. Ureteroscopy and transureteral lithotripsy (TUL) were performed five minutes after irrigation. Results. The mean duration of TUL was 4.2±2.61 min and 8.4±2.9 min for control and case groups, respectively. The successful rate was 95% and 76.1% in case and control groups, respectively. Further extracorporeal shock wave lithotripsy (SWL) was performed in 5% and 30% for patients in case and control groups, respectively. Conclusion. Aminophylline facilitated ureteroscopy and increased the success rate in the treatment of renal colic using TUL. No significant complications from post-TUL were observed. Using aminophylline carries several advantages such as reducing procedure duration, decreasing the need for ureteral and double-J catheter, and reducing stone migration to the kidney and use of SWL.
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spelling doaj-art-b6eba6aeefa243f08ced064197a2d9032025-02-03T07:23:52ZengWileyAdvances in Urology1687-63691687-63772012-01-01201210.1155/2012/727843727843The Effects of Local Administration of Aminophylline on Transureteral LithotripsyAyyoub Barzegarnezhad0Abolfazl Firouzian1Seyed Abdollah Emadi2Nadali Mousanejad3Roksana Bakhshali4Department of Urology, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, IranDepartment of Anesthesiology, Faculty of Medicine, Mazandaran University of Medical Science, Sari, IranDepartment of Anesthesiology, Faculty of Medicine, Mazandaran University of Medical Science, Sari, IranDepartment of Urology, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, IranStudent Research Committee, Faculty of Medicine, Mazandaran University of Medical Science, Sari, IranIntroduction. Urinary stone is a common cause of urinary tract disease. Stone excretion using ureteroscope is effective in inferior ureter. The aim of this study was to investigate the effects of aminophylline on ureteral spasm during ureteroscopy in acute phase of renal colic. Methods. In this double-blind randomized clinical trial, 120 patients with ureteral stones were enrolled and randomized into two groups. The bladder was drained and then received a 150 mL irrigation solution. Irrigation solution was saline and saline plus 10 mL aminophylline at 250 mg dose for control and case groups, respectively. Ureteroscopy and transureteral lithotripsy (TUL) were performed five minutes after irrigation. Results. The mean duration of TUL was 4.2±2.61 min and 8.4±2.9 min for control and case groups, respectively. The successful rate was 95% and 76.1% in case and control groups, respectively. Further extracorporeal shock wave lithotripsy (SWL) was performed in 5% and 30% for patients in case and control groups, respectively. Conclusion. Aminophylline facilitated ureteroscopy and increased the success rate in the treatment of renal colic using TUL. No significant complications from post-TUL were observed. Using aminophylline carries several advantages such as reducing procedure duration, decreasing the need for ureteral and double-J catheter, and reducing stone migration to the kidney and use of SWL.http://dx.doi.org/10.1155/2012/727843
spellingShingle Ayyoub Barzegarnezhad
Abolfazl Firouzian
Seyed Abdollah Emadi
Nadali Mousanejad
Roksana Bakhshali
The Effects of Local Administration of Aminophylline on Transureteral Lithotripsy
Advances in Urology
title The Effects of Local Administration of Aminophylline on Transureteral Lithotripsy
title_full The Effects of Local Administration of Aminophylline on Transureteral Lithotripsy
title_fullStr The Effects of Local Administration of Aminophylline on Transureteral Lithotripsy
title_full_unstemmed The Effects of Local Administration of Aminophylline on Transureteral Lithotripsy
title_short The Effects of Local Administration of Aminophylline on Transureteral Lithotripsy
title_sort effects of local administration of aminophylline on transureteral lithotripsy
url http://dx.doi.org/10.1155/2012/727843
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