Responsible research in health disparities using the Adolescent Brain Cognitive DevelopmentSM (ABCD) study
Purpose: The Adolescent Brain Cognitive DevelopmentSM (ABCD) Study is the largest longitudinal study on brain development and adolescent health in the United States. The study includes a sociodemographically diverse cohort of nearly 12,000 youth born 2005–2009, with an open science model of making d...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-01-01
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| Series: | Developmental Cognitive Neuroscience |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1878929324001580 |
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| author | MR Gonzalez C Cardenas-Iniguez DE Linares S Wonnum K Bagot EJ White A Cuan S DiMatteo YD Akiel P Lindsley JC Harris E Perez-Amparan TD Powell Comité Organizador Latino de City Heights (COLCH) G Dowling D Alkire WK Thompson TM Murray |
| author_facet | MR Gonzalez C Cardenas-Iniguez DE Linares S Wonnum K Bagot EJ White A Cuan S DiMatteo YD Akiel P Lindsley JC Harris E Perez-Amparan TD Powell Comité Organizador Latino de City Heights (COLCH) G Dowling D Alkire WK Thompson TM Murray |
| author_sort | MR Gonzalez |
| collection | DOAJ |
| description | Purpose: The Adolescent Brain Cognitive DevelopmentSM (ABCD) Study is the largest longitudinal study on brain development and adolescent health in the United States. The study includes a sociodemographically diverse cohort of nearly 12,000 youth born 2005–2009, with an open science model of making data rapidly available to the scientific community. The ABCD Study® data has been used in over 1100 peer-reviewed publications since its first data release in 2018. The dataset contains a broad scope and comprehensive set of measures of youths’ behavioral, health, and brain outcomes, as well as extensive contextual and environmental measures that map onto the social determinants of health (SDOH). Understanding the impact of SDOH on the developmental trajectories of youth will help to address early lifecourse health inequities that lead to disparities later in life. However, the open science model and extensive use of ABCD data highlight the need for guidance on appropriate, responsible, and equitable use of the data. Design Methods: Our conceptual framework integrates the National Institute on Minority Health and Health Disparities (NIMHD) Research Framework with strength-based and data equity perspectives. We use this framework to articulate best practices and methods for investigations that aim to identify the multilevel pathways by which structural and systemic inequities impact adolescent health trajectories. Results: Using our conceptual model, we provide recommendations for equitable health disparities research using ABCD Study data. We identify over fifty ABCD measures that can encompass SDOH across five levels of influence: individual, interpersonal, school, community, and societal. We expand the societal level to acknowledge structural discrimination as the root cause of systemic and structural inequities resulting in health disparities among marginalized youth. We apply the methodological recommendations in an example data analysis using a multi-level approach that integrates strength-based and data equity perspectives to elucidate pathways by which social and structural inequities may influence cognitive decision making in youth. We conclude with recommendations for strengthening the utility of ABCD data for health disparities research now and in the future. Conclusion: Adolescence is a critical period of development with subsequent ramifications for health outcomes across the lifespan. Thus, understanding SDOH among diverse youth can inform prevention interventions before the emergence of health disparities in adulthood. |
| format | Article |
| id | doaj-art-b6c8c72bfd68483fbea6e1740bc8ef39 |
| institution | Kabale University |
| issn | 1878-9293 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Developmental Cognitive Neuroscience |
| spelling | doaj-art-b6c8c72bfd68483fbea6e1740bc8ef392025-01-22T05:41:19ZengElsevierDevelopmental Cognitive Neuroscience1878-92932025-01-0171101497Responsible research in health disparities using the Adolescent Brain Cognitive DevelopmentSM (ABCD) studyMR Gonzalez0C Cardenas-Iniguez1DE Linares2S Wonnum3K Bagot4EJ White5A Cuan6S DiMatteo7YD Akiel8P Lindsley9JC Harris10E Perez-Amparan11TD Powell12Comité Organizador Latino de City Heights (COLCH)13G Dowling14D Alkire15WK Thompson16TM Murray17The Ohio State University OSU - (MRG), USAUniversity of Southern California (CCI, YDA), USANational Institute on Minority Health and Health Disparities (SW, DEL), USANational Institute on Minority Health and Health Disparities (SW, DEL), USAUniversity of California Los Angeles (KB), USALaureate Institute for Brain Research (EJW, WKT), USAFlorida International University (AC), USAUniversity of California San Diego UCSD - (SD, COLCH), USAUniversity of Southern California (CCI, YDA), USAWashington University (PL, TDP), USAUniversity of Wisconsin-Milwaukee (JCH), USASRI International (EPA), USAWashington University (PL, TDP), USAUniversity of California San Diego UCSD - (SD, COLCH), USANational Institute on Drug Abuse (GD, DA, TMM), USANational Institute on Drug Abuse (GD, DA, TMM), USALaureate Institute for Brain Research (EJW, WKT), USANational Institute on Drug Abuse (GD, DA, TMM), USA; Correspondence to: Scientific Advisor, National Institute on Drug Abuse, USA.Purpose: The Adolescent Brain Cognitive DevelopmentSM (ABCD) Study is the largest longitudinal study on brain development and adolescent health in the United States. The study includes a sociodemographically diverse cohort of nearly 12,000 youth born 2005–2009, with an open science model of making data rapidly available to the scientific community. The ABCD Study® data has been used in over 1100 peer-reviewed publications since its first data release in 2018. The dataset contains a broad scope and comprehensive set of measures of youths’ behavioral, health, and brain outcomes, as well as extensive contextual and environmental measures that map onto the social determinants of health (SDOH). Understanding the impact of SDOH on the developmental trajectories of youth will help to address early lifecourse health inequities that lead to disparities later in life. However, the open science model and extensive use of ABCD data highlight the need for guidance on appropriate, responsible, and equitable use of the data. Design Methods: Our conceptual framework integrates the National Institute on Minority Health and Health Disparities (NIMHD) Research Framework with strength-based and data equity perspectives. We use this framework to articulate best practices and methods for investigations that aim to identify the multilevel pathways by which structural and systemic inequities impact adolescent health trajectories. Results: Using our conceptual model, we provide recommendations for equitable health disparities research using ABCD Study data. We identify over fifty ABCD measures that can encompass SDOH across five levels of influence: individual, interpersonal, school, community, and societal. We expand the societal level to acknowledge structural discrimination as the root cause of systemic and structural inequities resulting in health disparities among marginalized youth. We apply the methodological recommendations in an example data analysis using a multi-level approach that integrates strength-based and data equity perspectives to elucidate pathways by which social and structural inequities may influence cognitive decision making in youth. We conclude with recommendations for strengthening the utility of ABCD data for health disparities research now and in the future. Conclusion: Adolescence is a critical period of development with subsequent ramifications for health outcomes across the lifespan. Thus, understanding SDOH among diverse youth can inform prevention interventions before the emergence of health disparities in adulthood.http://www.sciencedirect.com/science/article/pii/S1878929324001580Health disparities researchResponsible data useSocial determinants of healthAdolescent health |
| spellingShingle | MR Gonzalez C Cardenas-Iniguez DE Linares S Wonnum K Bagot EJ White A Cuan S DiMatteo YD Akiel P Lindsley JC Harris E Perez-Amparan TD Powell Comité Organizador Latino de City Heights (COLCH) G Dowling D Alkire WK Thompson TM Murray Responsible research in health disparities using the Adolescent Brain Cognitive DevelopmentSM (ABCD) study Developmental Cognitive Neuroscience Health disparities research Responsible data use Social determinants of health Adolescent health |
| title | Responsible research in health disparities using the Adolescent Brain Cognitive DevelopmentSM (ABCD) study |
| title_full | Responsible research in health disparities using the Adolescent Brain Cognitive DevelopmentSM (ABCD) study |
| title_fullStr | Responsible research in health disparities using the Adolescent Brain Cognitive DevelopmentSM (ABCD) study |
| title_full_unstemmed | Responsible research in health disparities using the Adolescent Brain Cognitive DevelopmentSM (ABCD) study |
| title_short | Responsible research in health disparities using the Adolescent Brain Cognitive DevelopmentSM (ABCD) study |
| title_sort | responsible research in health disparities using the adolescent brain cognitive developmentsm abcd study |
| topic | Health disparities research Responsible data use Social determinants of health Adolescent health |
| url | http://www.sciencedirect.com/science/article/pii/S1878929324001580 |
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