TrimNN: characterizing cellular community motifs for studying multicellular topological organization in complex tissues

Abstract The spatial organization of cells plays a pivotal role in shaping tissue functions and phenotypes in various biological systems and diseased microenvironments. However, the topological principles governing interactions among cell types within spatial patterns remain poorly understood. Here,...

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Bibliographic Details
Main Authors: Yang Yu, Shuang Wang, Jinpu Li, Meichen Yu, Kyle McCrocklin, Jing-Qiong Kang, Anjun Ma, Qin Ma, Dong Xu, Juexin Wang
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-63141-7
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