Recent Advances in Vaginal Atresia: A Literature Review
Vaginal atresia is a rare anomaly of the female reproductive tract that significantly impacts women’s reproductive health and quality of life. Although there has been relatively extensive research on the clinical manifestations and differential diagnosis of vaginal atresia, there is a paucity of lit...
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MDPI AG
2025-01-01
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| author | Xijuan Lin Jia Kang Lan Zhu |
| author_facet | Xijuan Lin Jia Kang Lan Zhu |
| author_sort | Xijuan Lin |
| collection | DOAJ |
| description | Vaginal atresia is a rare anomaly of the female reproductive tract that significantly impacts women’s reproductive health and quality of life. Although there has been relatively extensive research on the clinical manifestations and differential diagnosis of vaginal atresia, there is a paucity of literature specifically addressing the genetic background, treatment protocols, and psychological status of patients with vaginal atresia, indicating a need for further investigation. In this context, this article systematically reviews the epidemiological characteristics of vaginal atresia and explores its etiology from multiple perspectives, including developmental processes, genetic factors, and environmental factors, emphasizing the importance of genetic susceptibility and environmental interactions in the pathogenesis of the condition. Building upon a summary of the clinical presentations, classification, and diagnostic methods of vaginal atresia, this article provides an overview of current treatment strategies for both partial vaginal atresia and complete vaginal atresia, discusses the psychological status of affected patients, and examines fertility outcomes and sexual function. The aim is to offer insights and recommendations for future research on vaginal atresia, ultimately striving to enhance the quality of life for affected individuals. |
| format | Article |
| id | doaj-art-b6b7d4a1951946aca622a344651ae9c4 |
| institution | Kabale University |
| issn | 2227-9059 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | MDPI AG |
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| series | Biomedicines |
| spelling | doaj-art-b6b7d4a1951946aca622a344651ae9c42025-01-24T13:24:06ZengMDPI AGBiomedicines2227-90592025-01-0113112810.3390/biomedicines13010128Recent Advances in Vaginal Atresia: A Literature ReviewXijuan Lin0Jia Kang1Lan Zhu2Department of Obstetrics and Gynecology, National Clinical Research Center for Obstetric and Gynecologic Diseases, Peking Union Medical College Hospital, State Key Laboratory for Complex Severe and Rare Diseases, Peking Union Medical College, Chinese Academy of Medical Sciences, No. 1 Shuaifuyuan, Beijing 100005, ChinaDepartment of Obstetrics and Gynecology, National Clinical Research Center for Obstetric and Gynecologic Diseases, Peking Union Medical College Hospital, State Key Laboratory for Complex Severe and Rare Diseases, Peking Union Medical College, Chinese Academy of Medical Sciences, No. 1 Shuaifuyuan, Beijing 100005, ChinaDepartment of Obstetrics and Gynecology, National Clinical Research Center for Obstetric and Gynecologic Diseases, Peking Union Medical College Hospital, State Key Laboratory for Complex Severe and Rare Diseases, Peking Union Medical College, Chinese Academy of Medical Sciences, No. 1 Shuaifuyuan, Beijing 100005, ChinaVaginal atresia is a rare anomaly of the female reproductive tract that significantly impacts women’s reproductive health and quality of life. Although there has been relatively extensive research on the clinical manifestations and differential diagnosis of vaginal atresia, there is a paucity of literature specifically addressing the genetic background, treatment protocols, and psychological status of patients with vaginal atresia, indicating a need for further investigation. In this context, this article systematically reviews the epidemiological characteristics of vaginal atresia and explores its etiology from multiple perspectives, including developmental processes, genetic factors, and environmental factors, emphasizing the importance of genetic susceptibility and environmental interactions in the pathogenesis of the condition. Building upon a summary of the clinical presentations, classification, and diagnostic methods of vaginal atresia, this article provides an overview of current treatment strategies for both partial vaginal atresia and complete vaginal atresia, discusses the psychological status of affected patients, and examines fertility outcomes and sexual function. The aim is to offer insights and recommendations for future research on vaginal atresia, ultimately striving to enhance the quality of life for affected individuals.https://www.mdpi.com/2227-9059/13/1/128vaginal atresiaresearch advancesgenetic factorstreatment strategiesfertility outcomes |
| spellingShingle | Xijuan Lin Jia Kang Lan Zhu Recent Advances in Vaginal Atresia: A Literature Review Biomedicines vaginal atresia research advances genetic factors treatment strategies fertility outcomes |
| title | Recent Advances in Vaginal Atresia: A Literature Review |
| title_full | Recent Advances in Vaginal Atresia: A Literature Review |
| title_fullStr | Recent Advances in Vaginal Atresia: A Literature Review |
| title_full_unstemmed | Recent Advances in Vaginal Atresia: A Literature Review |
| title_short | Recent Advances in Vaginal Atresia: A Literature Review |
| title_sort | recent advances in vaginal atresia a literature review |
| topic | vaginal atresia research advances genetic factors treatment strategies fertility outcomes |
| url | https://www.mdpi.com/2227-9059/13/1/128 |
| work_keys_str_mv | AT xijuanlin recentadvancesinvaginalatresiaaliteraturereview AT jiakang recentadvancesinvaginalatresiaaliteraturereview AT lanzhu recentadvancesinvaginalatresiaaliteraturereview |