Direct-to-implant Prepectoral Breast Reconstruction in Women Older Than 65 Years: Analysis of Safety and Patient-reported Outcome

Background:. Immediate breast reconstruction following mastectomy has many proven advantages. Although more than half of the patients with breast cancer in the United States are older than 65 years of age, breast reconstruction rates in this age group are low. The goal of this study was to evaluate...

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Main Authors: Adi Maisel Lotan, MD, Yotam Teldan, MD, Ronen Toledano, MD, Shahar Talisman, MD, Shalom Strano, MD, Hadar Goldvaser, MD, Tal Zobok, MD, Yoav Gronovich, MD, MBA
Format: Article
Language:English
Published: Wolters Kluwer 2025-03-01
Series:Plastic and Reconstructive Surgery, Global Open
Online Access:http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000006647
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author Adi Maisel Lotan, MD
Yotam Teldan, MD
Ronen Toledano, MD
Shahar Talisman, MD
Shalom Strano, MD
Hadar Goldvaser, MD
Tal Zobok, MD
Yoav Gronovich, MD, MBA
author_facet Adi Maisel Lotan, MD
Yotam Teldan, MD
Ronen Toledano, MD
Shahar Talisman, MD
Shalom Strano, MD
Hadar Goldvaser, MD
Tal Zobok, MD
Yoav Gronovich, MD, MBA
author_sort Adi Maisel Lotan, MD
collection DOAJ
description Background:. Immediate breast reconstruction following mastectomy has many proven advantages. Although more than half of the patients with breast cancer in the United States are older than 65 years of age, breast reconstruction rates in this age group are low. The goal of this study was to evaluate safety and patient satisfaction of direct-to-implant (DTI) prepectoral breast reconstruction in women older than 65 years of age. Methods:. This was a retrospective, single-center study of 56 women (56 breasts) undergoing DTI prepectoral breast reconstruction. Twenty-eight patients were older than the age of 65 years and 28 were younger. Groups were matched for surgical procedure, smoking status, body mass index, and history of radiation therapy. Outcomes were compared between groups, and possible correlations were studied. Results:. Twelve patients older than 65 years of age had hypertension (P = 0.007). Perioperative pain management, major complications, total number of surgical complications, reconstruction failure, and duration of hospitalization were similar in both groups. More advanced age was correlated with higher psychosocial well-being, sexual well-being and satisfaction with breasts on the BREAST-Q scale. Median follow-up was 11.5 months (older) and 23 months (younger). Conclusions:. Prepectoral DTI breast reconstruction in women older than 65 years of age is safe, reproducible, has high patient satisfaction, and may be performed in this patient cohort.
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spelling doaj-art-b6acd10d60d049c7acfde301e43a7dd02025-08-20T03:40:17ZengWolters KluwerPlastic and Reconstructive Surgery, Global Open2169-75742025-03-01133e664710.1097/GOX.0000000000006647202503000-00086Direct-to-implant Prepectoral Breast Reconstruction in Women Older Than 65 Years: Analysis of Safety and Patient-reported OutcomeAdi Maisel Lotan, MD0Yotam Teldan, MD1Ronen Toledano, MD2Shahar Talisman, MD3Shalom Strano, MD4Hadar Goldvaser, MD5Tal Zobok, MD6Yoav Gronovich, MD, MBA7From the * Department of Plastic and Reconstructive Surgery, Shaare Zedek Medical Center, Jerusalem, IsraelFrom the * Department of Plastic and Reconstructive Surgery, Shaare Zedek Medical Center, Jerusalem, IsraelFrom the * Department of Plastic and Reconstructive Surgery, Shaare Zedek Medical Center, Jerusalem, IsraelFrom the * Department of Plastic and Reconstructive Surgery, Shaare Zedek Medical Center, Jerusalem, Israel† Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel† Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel† Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, IsraelFrom the * Department of Plastic and Reconstructive Surgery, Shaare Zedek Medical Center, Jerusalem, IsraelBackground:. Immediate breast reconstruction following mastectomy has many proven advantages. Although more than half of the patients with breast cancer in the United States are older than 65 years of age, breast reconstruction rates in this age group are low. The goal of this study was to evaluate safety and patient satisfaction of direct-to-implant (DTI) prepectoral breast reconstruction in women older than 65 years of age. Methods:. This was a retrospective, single-center study of 56 women (56 breasts) undergoing DTI prepectoral breast reconstruction. Twenty-eight patients were older than the age of 65 years and 28 were younger. Groups were matched for surgical procedure, smoking status, body mass index, and history of radiation therapy. Outcomes were compared between groups, and possible correlations were studied. Results:. Twelve patients older than 65 years of age had hypertension (P = 0.007). Perioperative pain management, major complications, total number of surgical complications, reconstruction failure, and duration of hospitalization were similar in both groups. More advanced age was correlated with higher psychosocial well-being, sexual well-being and satisfaction with breasts on the BREAST-Q scale. Median follow-up was 11.5 months (older) and 23 months (younger). Conclusions:. Prepectoral DTI breast reconstruction in women older than 65 years of age is safe, reproducible, has high patient satisfaction, and may be performed in this patient cohort.http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000006647
spellingShingle Adi Maisel Lotan, MD
Yotam Teldan, MD
Ronen Toledano, MD
Shahar Talisman, MD
Shalom Strano, MD
Hadar Goldvaser, MD
Tal Zobok, MD
Yoav Gronovich, MD, MBA
Direct-to-implant Prepectoral Breast Reconstruction in Women Older Than 65 Years: Analysis of Safety and Patient-reported Outcome
Plastic and Reconstructive Surgery, Global Open
title Direct-to-implant Prepectoral Breast Reconstruction in Women Older Than 65 Years: Analysis of Safety and Patient-reported Outcome
title_full Direct-to-implant Prepectoral Breast Reconstruction in Women Older Than 65 Years: Analysis of Safety and Patient-reported Outcome
title_fullStr Direct-to-implant Prepectoral Breast Reconstruction in Women Older Than 65 Years: Analysis of Safety and Patient-reported Outcome
title_full_unstemmed Direct-to-implant Prepectoral Breast Reconstruction in Women Older Than 65 Years: Analysis of Safety and Patient-reported Outcome
title_short Direct-to-implant Prepectoral Breast Reconstruction in Women Older Than 65 Years: Analysis of Safety and Patient-reported Outcome
title_sort direct to implant prepectoral breast reconstruction in women older than 65 years analysis of safety and patient reported outcome
url http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000006647
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