Effect of Maintenance Azithromycin on Established Bronchiolitis Obliterans Syndrome in Lung Transplant Patients

BACKGROUND: Bronchiolitis obliterans syndrome (BOS), the main cause of late mortality following lung transplantation, is defined as an irreversible decline in forced expiratory volume in 1 s (FEV1).Previous studies using azithromycin for BOS in lung transplant patients have demonstrated a potential...

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Main Authors: Nancy R Porhownik, Wael Batobara, Wayne Kepron, Helmut W Unruh, Zoheir Bshouty
Format: Article
Language:English
Published: Wiley 2008-01-01
Series:Canadian Respiratory Journal
Online Access:http://dx.doi.org/10.1155/2008/158681
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author Nancy R Porhownik
Wael Batobara
Wayne Kepron
Helmut W Unruh
Zoheir Bshouty
author_facet Nancy R Porhownik
Wael Batobara
Wayne Kepron
Helmut W Unruh
Zoheir Bshouty
author_sort Nancy R Porhownik
collection DOAJ
description BACKGROUND: Bronchiolitis obliterans syndrome (BOS), the main cause of late mortality following lung transplantation, is defined as an irreversible decline in forced expiratory volume in 1 s (FEV1).Previous studies using azithromycin for BOS in lung transplant patients have demonstrated a potential reversibility of the decline in FEV1.
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institution Kabale University
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language English
publishDate 2008-01-01
publisher Wiley
record_format Article
series Canadian Respiratory Journal
spelling doaj-art-b6a047fe691b4c0eb8775400a28423f82025-02-03T01:06:13ZengWileyCanadian Respiratory Journal1198-22412008-01-0115419920210.1155/2008/158681Effect of Maintenance Azithromycin on Established Bronchiolitis Obliterans Syndrome in Lung Transplant PatientsNancy R Porhownik0Wael Batobara1Wayne Kepron2Helmut W Unruh3Zoheir Bshouty4Department of Respiratory Medicine, University of Manitoba, Winnipeg, Manitoba, CanadaDepartment of Respiratory Medicine, University of Manitoba, Winnipeg, Manitoba, CanadaDepartment of Respiratory Medicine, University of Manitoba, Winnipeg, Manitoba, CanadaDepartment of Thoracic Surgery, University of Manitoba, Winnipeg, Manitoba, CanadaDepartment of Respiratory Medicine, University of Manitoba, Winnipeg, Manitoba, CanadaBACKGROUND: Bronchiolitis obliterans syndrome (BOS), the main cause of late mortality following lung transplantation, is defined as an irreversible decline in forced expiratory volume in 1 s (FEV1).Previous studies using azithromycin for BOS in lung transplant patients have demonstrated a potential reversibility of the decline in FEV1.http://dx.doi.org/10.1155/2008/158681
spellingShingle Nancy R Porhownik
Wael Batobara
Wayne Kepron
Helmut W Unruh
Zoheir Bshouty
Effect of Maintenance Azithromycin on Established Bronchiolitis Obliterans Syndrome in Lung Transplant Patients
Canadian Respiratory Journal
title Effect of Maintenance Azithromycin on Established Bronchiolitis Obliterans Syndrome in Lung Transplant Patients
title_full Effect of Maintenance Azithromycin on Established Bronchiolitis Obliterans Syndrome in Lung Transplant Patients
title_fullStr Effect of Maintenance Azithromycin on Established Bronchiolitis Obliterans Syndrome in Lung Transplant Patients
title_full_unstemmed Effect of Maintenance Azithromycin on Established Bronchiolitis Obliterans Syndrome in Lung Transplant Patients
title_short Effect of Maintenance Azithromycin on Established Bronchiolitis Obliterans Syndrome in Lung Transplant Patients
title_sort effect of maintenance azithromycin on established bronchiolitis obliterans syndrome in lung transplant patients
url http://dx.doi.org/10.1155/2008/158681
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